Ace+Method+Development+Kits
Catalog Number:
(10349-276)
Supplier:
Bioss
Description:
The survival and development of central neurons require the supply of trophic factors by glial cells. The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, which are glia-derived trophic factors synthesized by 3PGDH (1). 3PGDH protein is 544 amino acids in length. Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2.1 kb mRNA, which is highly expressed in prostate, testis, ovary, brain, liver, kidney, and pancreas, and weakly expressed in thymus, colon, and heart, and 710 bp mRNA, which is highly expressed in heart and skeletal muscle (2). 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2). 3PGDH protein is also highly expressed in adult and fetal brain tissues (3). 3PGDH protein plays an important role in the metabolism, development, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, psychomotor retardation, and seizures (3).
Supplier:
Biotium
Description:
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number:
(10461-974)
Supplier:
Bioss
Description:
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Supplier:
TCI America
Description:
CAS Number: 29823-18-5
MDL Number: MFCD00037103 Molecular Formula: C9H17BrO2 Molecular Weight: 237.14 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 145 Specific Gravity (20/20): 1.22
Catalog Number:
(TCC0915-025ML)
Supplier:
TCI America
Description:
CAS Number: 150-84-5
MDL Number: MFCD00015039 Molecular Formula: C12H22O2 Molecular Weight: 198.31 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 173 Flash Point (°C): 112 Specific Gravity (20/20): 0.89
Catalog Number:
(TCD1842-100G)
Supplier:
TCI America
Description:
CAS Number: 74-94-2
MDL Number: MFCD00051068 Molecular Formula: C2H10BN Molecular Weight: 58.92 Purity/Analysis Method: >95.0% (T) Form: Crystal Melting point (°C): 37 Flash Point (°C): 43 Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
CAS Number: 86953-79-9
MDL Number: MFCD00216581 Molecular Formula: C9H17NO2 Molecular Weight: 171.24 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 75 Flash Point (°C): 86 Specific Gravity (20/20): 0.98
Supplier:
TCI America
Description:
CAS Number: 2356-16-3
MDL Number: MFCD00134400 Molecular Formula: C8H16FO5P Molecular Weight: 242.18 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 200 Flash Point (°C): 73 Specific Gravity (20/20): 1.19
Catalog Number:
(TCD4372-200MG)
Supplier:
TCI America
Description:
CAS Number: 3868-03-9
MDL Number: MFCD18643031 Molecular Formula: C6H8O4 Molecular Weight: 144.13 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 69 Specific rotation [a]20/D: -35 deg (C=1, MeOH)
Supplier:
TCI America
Description:
CAS Number: 58859-46-4
MDL Number: MFCD00006484 Molecular Formula: C8H16N2O2 Molecular Weight: 172.23 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Flash Point (°C): 78 Specific Gravity (20/20): 1.08
Catalog Number:
(TCD2744-1G)
Supplier:
TCI America
Description:
CAS Number: 31249-95-3
MDL Number: MFCD00005109 Molecular Formula: C10H22N2O3 Molecular Weight: 218.30 Purity/Analysis Method: >96.0% (GC) Form: Crystal Melting point (°C): 89
Supplier:
TCI America
Description:
CAS Number: 5137-52-0
MDL Number: MFCD00027272 Molecular Formula: C13H18O2 Molecular Weight: 206.29 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 269 Specific Gravity (20/20): 0.98
Supplier:
TCI America
Description:
CAS Number: 186769-18-6
MDL Number: MFCD06797064 Molecular Formula: C20H28N2 Molecular Weight: 296.46 Purity/Analysis Method: >97.0% (GC,T) Form: Crystal Melting point (°C): 85 Specific rotation [a]20/D: -202 deg (C=1, CH2Cl2)
Supplier:
TCI America
Description:
CAS Number: 33100-27-5
MDL Number: MFCD00005110 Molecular Formula: C10H20O5 Molecular Weight: 220.27 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 116 Melting point (°C): -20 Flash Point (°C): 113 Specific Gravity (20/20): 1.11
Catalog Number:
(TCA5568-100MG)
Supplier:
TCI America
Description:
[for HPLC Labeling]
CAS Number: 163927-31-9 MDL Number: MFCD00671493 Molecular Formula: C13H15N5O3S2 Molecular Weight: 353.42 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Specific rotation [a]20/D: -285 deg (C=0.4, CH3CN) Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
CAS Number: 6283-63-2
MDL Number: MFCD00012993 Molecular Formula: C10H16N2 Molecular Weight: 262.32 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 185
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