Ace+Method+Development+Kits
Catalog Number:
(10412-894)
Supplier:
Bioss
Description:
Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate and divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid (one too many or too few chromatids), the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers.
Catalog Number:
(10464-118)
Supplier:
Bioss
Description:
Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Supplier:
TCI America
Description:
CAS Number: 349-03-1
MDL Number: MFCD00014685 Molecular Formula: C7H3BrF3NO2 Molecular Weight: 270.01 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 105 Flash Point (°C): 113 Specific Gravity (20/20): 1.80
Catalog Number:
(TCO0246-025ML)
Supplier:
TCI America
Description:
CAS Number: 39815-78-6
MDL Number: MFCD00191568 Molecular Formula: C8H14O3 Molecular Weight: 158.20 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 95 Flash Point (°C): 95 Specific Gravity (20/20): 0.99
Catalog Number:
(TCA1444-005G)
Supplier:
TCI America
Description:
CAS Number: 16212-05-8
MDL Number: MFCD00014739 Molecular Formula: C9H10O2S Molecular Weight: 182.24 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 128 Flash Point (°C): 110 Specific Gravity (20/20): 1.19
Supplier:
TCI America
Description:
CAS Number: 133-08-4
MDL Number: MFCD00009170 Molecular Formula: C11H20O4 Molecular Weight: 216.28 Purity/Analysis Method: >99.0% (GC) Form: Clear Liquid Boiling point (°C): 240 Flash Point (°C): 94 Specific Gravity (20/20): 0.98
Catalog Number:
(TCM0448-025ML)
Supplier:
TCI America
Description:
CAS Number: 536-50-5
MDL Number: MFCD00016860 Molecular Formula: C9H12O Molecular Weight: 136.19 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 220 Flash Point (°C): 107 Specific Gravity (20/20): 0.99
Catalog Number:
(TCA0455-100ML)
Supplier:
TCI America
Description:
CAS Number: 463-04-7
MDL Number: MFCD00036132 Molecular Formula: C5H11NO2 Molecular Weight: 117.15 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 104 Flash Point (°C): -18 Specific Gravity (20/20): 0.88 Storage Temperature: 0-10°C
Catalog Number:
(TCL0238-1G)
Supplier:
TCI America
Description:
CAS Number: 100986-89-8
MDL Number: MFCD04039905 Molecular Formula: C13H9F2NO4 Molecular Weight: 281.21 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Specific rotation [a]20/D: -64 deg (C=1, DMSO)
Supplier:
G-Biosciences
Description:
G-Biosciences' STRATEGY™ consists of numerous fractionation and chromatography techniques to aid researchers to develop a suitable purification system for specific and novel proteins
Supplier:
TCI America
Description:
CAS Number: 26607-51-2
MDL Number: MFCD00063126 Molecular Formula: C11H13NO4 Molecular Weight: 223.23 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 85 Specific rotation [a]20/D: 15 deg (C=2, AcOH)
Catalog Number:
(TCC2424-1G)
Supplier:
TCI America
Description:
CAS Number: 100306-34-1
MDL Number: MFCD00013309 Molecular Formula: C9H11ClO Molecular Weight: 170.64 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 59 Specific rotation [a]20/D: -25 deg (C=1, CHCl3)
Catalog Number:
(89360-292)
Supplier:
Genetex
Description:
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Supplier:
TCI America
Description:
(stabilized with MEHQ)
CAS Number: 4813-57-4 MDL Number: MFCD00015091 Molecular Formula: C21H40O2 Molecular Weight: 324.55 Purity/Analysis Method: >97.0% (GC) Form: Crystal Melting point (°C): 28 Flash Point (°C): 191
Catalog Number:
(TCA0813-025ML)
Supplier:
TCI America
Description:
CAS Number: 13562-81-7
MDL Number: MFCD00059415 Molecular Formula: C9H16O3 Molecular Weight: 172.22 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 213 Specific Gravity (20/20): 0.97
Supplier:
TCI America
Description:
CAS Number: 2417-04-1
MDL Number: MFCD00094737 Molecular Formula: C16H18O2 Molecular Weight: 242.32 Purity/Analysis Method: >98.0% (GC) Form: Crystal Color: Very Pale Yellow Melting point (°C): 225
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