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Ace+Method+Development+Kits
Catalog Number:
(10110-782)
Supplier:
Prosci
Description:
C20orf141 is a single-pass membrane protein. The exact function of C20orf141 remains unknown.
Catalog Number:
(10110-966)
Supplier:
Prosci
Description:
C17orf81 belongs to the ELP5 family. C17orf81 may be involved in TP53-mediated transcriptional regulation.
Catalog Number:
(75794-128)
Supplier:
Prosci
Description:
FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signaling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
Catalog Number:
(10798-038)
Supplier:
Prosci
Description:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
Catalog Number:
(TCD4514-200MG)
Supplier:
TCI America
Description:
CAS Number: 890704-02-6
MDL Number: MFCD19440927 Molecular Formula: C12H14Br3N3 Molecular Weight: 439.98 Purity/Analysis Method: >97.0% (GC) Form: Crystal
Catalog Number:
(10450-678)
Supplier:
Bioss
Description:
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
Catalog Number:
(TCG0342-2MG)
Supplier:
TCI America
Description:
CAS Number: 1304646-03-4
Molecular Formula: C28H48N4O18 Molecular Weight: 728.70 Purity/Analysis Method: >94.0% (HPLC) Form: Crystal Specific rotation [a]20/D: 32 deg (C=1, H2O) Storage Temperature: <0°C
Catalog Number:
(CAPIPA5-18079)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with mouse based on sequence homology. This gene encodes a member of the paired box family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in ttranslocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
Catalog Number:
(TCD4426-25G)
Supplier:
TCI America
Description:
CAS Number: 4176-55-0
MDL Number: MFCD01682880 Molecular Formula: C3H6O3S Molecular Weight: 122.14 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 54 Flash Point (°C): 84 Freezing point (°C): -14 Specific Gravity (20/20): 1.35
Catalog Number:
(10352-854)
Supplier:
Bioss
Description:
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Supplier:
TCI America
Description:
CAS Number: 174501-64-5
MDL Number: MFCD03093295 Molecular Formula: C8H15F6N2P Molecular Weight: 284.19 Purity/Analysis Method: >98.0% (HPLC,N) Form: Clear Liquid Specific Gravity (20/20): 1.37
Supplier:
TCI America
Description:
CAS Number: 187324-64-7
MDL Number: MFCD02093447 Molecular Formula: C25H29NO3S Molecular Weight: 423.57 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Specific rotation [a]20/D: -49 deg (C=2, EtOH)
Supplier:
Bachem Americas
Description:
The substrate EALFQ-pNA representing the 2C/3A cleavage site of human rhinovirus-14 (HRV-14) polyprotein was hydrolyzed by human rhinovirus-14 3C protease, which represents an attractive target for antiviral drug development. It exhibited a kcat/Km value of 840 M⁻¹s⁻¹.
Supplier:
TCI America
Description:
CAS Number: 86728-85-0
MDL Number: MFCD00211241 Molecular Formula: C6H11ClO3 Molecular Weight: 166.60 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 96 Flash Point (°C): 110 Specific Gravity (20/20): 1.19 Specific rotation [a]20/D: -14 deg (neat)
Supplier:
TCI America
Description:
CAS Number: 1571-86-4
MDL Number: MFCD01076591 Molecular Formula: C14H22 Molecular Weight: 190.33 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Specific Gravity (20/20): 0.86
Catalog Number:
(10106-090)
Supplier:
Prosci
Description:
BRD9 is a member of protein family that contains bromodomain. It is potentially related to cancer.
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