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Ace+Method+Development+Kits
Catalog Number:
(76078-984)
Supplier:
Bioss
Description:
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
Supplier:
TCI America
Description:
CAS Number: 79416-27-6
MDL Number: MFCD00012868 Molecular Formula: C6H11NO3 Molecular Weight: 181.62 Purity/Analysis Method: >98.0% (N,T) Form: Crystal Melting point (°C): 122 Storage Temperature: 0-10°C
Catalog Number:
(TCM2045-25G)
Supplier:
TCI America
Description:
CAS Number: 28940-11-6
MDL Number: MFCD07371373 Molecular Formula: C10H10O3 Molecular Weight: 178.19 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 91 Melting point (°C): 39 Storage Temperature: 0-10°C
Catalog Number:
(89358-884)
Supplier:
Genetex
Description:
Emx2 is a homeobox protein that is related to the Drosphila empty spiracles gene expressed in the cerebral cortex. Emx2 may function with Otx1/2 to specify cell destiny the developing central nervous system.
Supplier:
TCI America
Description:
CAS Number: 50525-27-4
MDL Number: MFCD00149670 Molecular Formula: C30H24Cl2N6Ru Molecular Weight: 640.53 Purity/Analysis Method: >98.0% (T) Form: Crystal Color: Yellow
Catalog Number:
(10386-720)
Supplier:
Bioss
Description:
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
Catalog Number:
(10386-714)
Supplier:
Bioss
Description:
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
Catalog Number:
(10386-690)
Supplier:
Bioss
Description:
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
Catalog Number:
(TCD0939-100ML)
Supplier:
TCI America
Description:
[for Spectrophotometry]
CAS Number: 68-12-2 MDL Number: MFCD00003284 Molecular Formula: C3H7NO Molecular Weight: 73.10 Purity/Analysis Method: >99.5% (GC) Form: Clear Liquid Boiling point (°C): 153 Melting point (°C): -61 Flash Point (°C): 60 Specific Gravity (20/20): 0.95
Catalog Number:
(75965-316)
Supplier:
Biotium
Description:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Catalog Number:
(75965-192)
Supplier:
Biotium
Description:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Catalog Number:
(10387-326)
Supplier:
Bioss
Description:
Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
Catalog Number:
(10373-486)
Supplier:
Bioss
Description:
Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. The Myt1 family, including Myt1 and Myt1L, exemplifies a class of neural sequence specific transcription factors that actively recruit HDACs to selected genes during CNS development.
Catalog Number:
(10374-480)
Supplier:
Bioss
Description:
Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. The Myt1 family, including Myt1 and Myt1L, exemplifies a class of neural sequence specific transcription factors that actively recruit HDACs to selected genes during CNS development.
Catalog Number:
(10374-482)
Supplier:
Bioss
Description:
Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. The Myt1 family, including Myt1 and Myt1L, exemplifies a class of neural sequence specific transcription factors that actively recruit HDACs to selected genes during CNS development.
Catalog Number:
(TCD2658-001G)
Supplier:
TCI America
Description:
CAS Number: 132747-20-7
MDL Number: MFCD01321289 Molecular Formula: C5H10N2 Molecular Weight: 259.97 Purity/Analysis Method: >98.0% (T) Form: Crystal Specific rotation [a]20/D: 21 deg (C=1, H2O)
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