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Ace+Method+Development+Kits
Catalog Number:
(76098-516)
Supplier:
Bioss
Description:
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (<i>in vitro</i>). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears. Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2.
Supplier:
Shenandoah Biotechnology
Description:
Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.
Catalog Number:
(TCB4219-1G)
Supplier:
TCI America
Description:
CAS Number: 58328-31-7
MDL Number: MFCD00093417 Molecular Formula: C36H24N2 Molecular Weight: 484.60 Purity/Analysis Method: >99.0% (HPLC,N) Form: Crystal Melting point (°C): 283 Lambda max.: 319 nm (CH2Cl2)
Catalog Number:
(TCS0827-200MG)
Supplier:
TCI America
Description:
[for Biochemical Research]
CAS Number: 82692-88-4 MDL Number: MFCD00063425 Molecular Formula: C11H17NO6S Molecular Weight: 313.30 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Color: White Storage Temperature: 0-10°C
Catalog Number:
(75789-394)
Supplier:
Prosci
Description:
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to BMP proteins, and can act the anti-BMP function, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. TWSG1 may be an important modulator of BMP-regulated cartilage development, chondrocyte differentiation and thymocyte development.
Catalog Number:
(10751-044)
Supplier:
Prosci
Description:
TRIM71 Antibody: TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.
Supplier:
TCI America
Description:
CAS Number: 26537-19-9
Molecular Formula: C12H16O2 Molecular Weight: 192.26 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 247 Specific Gravity (20/20): 1.01
Catalog Number:
(10104-378)
Supplier:
Prosci
Description:
The exact function of this protein remains unknown.
Catalog Number:
(10107-096)
Supplier:
Prosci
Description:
ZNF92 is a candidate transcription factor
Supplier:
TCI America
Description:
CAS Number: 155-04-4
MDL Number: MFCD00072234 Molecular Formula: C14H8N2S4Zn Molecular Weight: 397.85 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Color: White Melting point (°C): 325
Catalog Number:
(10109-508)
Supplier:
Prosci
Description:
TCP10L is a human leucine zipper protein with transcription inhibition activity.
Catalog Number:
(TCM2373-10MG)
Supplier:
TCI America
Description:
CAS Number: 267402-71-1
MDL Number: MFCD02683596 Molecular Formula: C24H28N6O2 Molecular Weight: 432.53 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 108 Storage Temperature: <0°C
Supplier:
TCI America
Description:
CAS Number: 269410-08-4
MDL Number: MFCD03453063 Molecular Formula: C9H15BN2O2 Molecular Weight: 194.04 Purity/Analysis Method: >97.0% (GC) Form: Crystal Color: White Melting point (°C): 147
Supplier:
TCI America
Description:
CAS Number: 28537-70-4
MDL Number: MFCD01318342 Molecular Formula: C12H12N2O4 Molecular Weight: 248.24 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Melting point (°C): 206 Storage Temperature: <0°C
Catalog Number:
(TCC1667-5G)
Supplier:
TCI America
Description:
CAS Number: 2267-25-6
MDL Number: MFCD00672965 Molecular Formula: C7H6ClFO Molecular Weight: 160.57 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 200 Flash Point (°C): 77 Specific Gravity (20/20): 1.30
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