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Ace+Method+Development+Kits
Catalog Number:
(75792-910)
Supplier:
Prosci
Description:
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
Catalog Number:
(10102-196)
Supplier:
Prosci
Description:
HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
Catalog Number:
(89366-370)
Supplier:
Genetex
Description:
Rabbit Polyclonal Antibody to LEF1
Catalog Number:
(10093-812)
Supplier:
Proteintech
Description:
RNF34(ring finger protein 34) has E3 ubiquitin-protein ligase activity and regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradationis.It is preferentially expressed in esophageal, gastric, and colorectal cancers, suggesting a possible association between RNF34 and the development of digestive tract cancers.Western blot results show the MW of 42-46kd,60kd,130kd.
Catalog Number:
(10087-300)
Supplier:
Proteintech
Description:
The GAD1(glutamate decarboxylase 1) gene encodes 67 kDa glutamic acid decarboxylase isoform (GAD67), the rate-limiting enzyme responsible for γ-aminobutyric acid (GABA) biosynthesis from glutamatic acid and the major GAD isoform in the human brain for early brain development. It is also potentially involved in variety of skin activities. It belongs to the group II decarboxylase family.
Catalog Number:
(10494-980)
Supplier:
Bioss
Description:
BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome.
Catalog Number:
(10086-686)
Supplier:
Proteintech
Description:
ETS variant gene 5(ETV5) belongs to the ETS oncogene family that shares a conserved peptide, ETS domain, which mediates sequence-specific DNA binding. ETV5 is a transcription factor and is required for spermatogonial stem cell self-renewal. ETV5 can be negatively regulated by COP1, a tumor suppressor. Also it has a role in branching morphogenesis in the developing kidney
Catalog Number:
(10083-548)
Supplier:
Proteintech
Description:
BCL11B, also named as CTIP2, RIT1, CTIP-2, ZNF856B and hRIT1-alpha, is a tumor-suppressor protein involved in T-cell lymphomas. It may function on the P53-signaling pathway. BCL11B is a key regulator of both differentiation and survival during thymocyte development. It tepress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. This antibody is specific to BCL11B.
Catalog Number:
(10752-204)
Supplier:
Prosci
Description:
SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types. SOX17 is also essential for acquisition and maintenance of arterial identity.
Catalog Number:
(10669-268)
Supplier:
Bioss
Description:
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SERPINB12 appears to be an inhibitor of trypsin-like serine proteinases, including mast cell tryptases.
Catalog Number:
(10672-198)
Supplier:
Bioss
Description:
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SERPINB12 appears to be an inhibitor of trypsin-like serine proteinases, including mast cell tryptases.
Catalog Number:
(10480-576)
Supplier:
Bioss
Description:
DHRSX (dehydrogenase/reductase SDR family member on chromosome X) is a 330 amino acid protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, DHRSX is an oxidoreductase that contains a coenzyme binding site and a substrate binding site, indicating a possible role in cellular metabolism. The gene that encodes DHRSX is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner's syndrome, Klinefelter's syndrome and Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Catalog Number:
(10480-572)
Supplier:
Bioss
Description:
DHRSX (dehydrogenase/reductase SDR family member on chromosome X) is a 330 amino acid protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, DHRSX is an oxidoreductase that contains a coenzyme binding site and a substrate binding site, indicating a possible role in cellular metabolism. The gene that encodes DHRSX is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner's syndrome, Klinefelter's syndrome and Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Catalog Number:
(10480-582)
Supplier:
Bioss
Description:
DHRSX (dehydrogenase/reductase SDR family member on chromosome X) is a 330 amino acid protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, DHRSX is an oxidoreductase that contains a coenzyme binding site and a substrate binding site, indicating a possible role in cellular metabolism. The gene that encodes DHRSX is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner's syndrome, Klinefelter's syndrome and Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Catalog Number:
(10102-646)
Supplier:
Prosci
Description:
The exact function of C6orf134 remains unknown.
Catalog Number:
(10103-632)
Supplier:
Prosci
Description:
The specific function of MPPE1 is not yet known.
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