Ace+Method+Development+Kits
Supplier:
Biotium
Description:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number:
(TCN0909-1G)
Supplier:
TCI America
Description:
CAS Number: 69984-73-2
MDL Number: MFCD00063300 Molecular Formula: C15H30O6 Molecular Weight: 306.40 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 70 Specific rotation [a]20/D: -27 deg (C=1, MeOH) Storage Temperature: <0°C
Catalog Number:
(77439-712)
Supplier:
Bioss
Description:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing MLL5. Mediates retinoic acid-induced granulopoiesis.
Catalog Number:
(76292-650)
Supplier:
BioFit
Description:
MVMT™ stands for Movement, for ergonomic seating. The chairs are developed to address the unique ergonomic needs and working postures of users in technical environments specifically for healthcare, laboratory, cleanroom and standing-desk applications.
Supplier:
BioFit
Description:
MVMT™ stands for Movement, for ergonomic seating. The chairs are developed to address the unique ergonomic needs and working postures of users in technical environments specifically for healthcare, laboratory, cleanroom and standing-desk applications.
Catalog Number:
(10366-618)
Supplier:
Bioss
Description:
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.
Catalog Number:
(10366-624)
Supplier:
Bioss
Description:
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.
Catalog Number:
(CAJTX171-3)
Catalog Number:
(TCA5009-005G)
Supplier:
TCI America
Description:
[Spectrophotometric reagent for U, Th, Zr and other metals, Indicator for the precipitation titration of SO4 with Ba]
CAS Number: 1668-00-4 MDL Number: MFCD00036695 Molecular Formula: C22H18As2N4O14S2 Molecular Weight: 776.36 Purity/Analysis Method: >95.0% (T)
Catalog Number:
(TCD0134-100G)
Supplier:
TCI America
Description:
CAS Number: 280-57-9
MDL Number: MFCD00006689 Molecular Formula: C6H12N2 Molecular Weight: 112.18 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 174 Melting point (°C): 155 Flash Point (°C): 70
Catalog Number:
(TCT1535-005G)
Supplier:
TCI America
Description:
[Trimethylsilylating Reagent]
CAS Number: 43112-38-5 MDL Number: MFCD00010197 Molecular Formula: C6H13NO2Si Molecular Weight: 159.26 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Very Pale Yellow Boiling point (°C): 122 Flash Point (°C): 76 Specific Gravity (20/20): 1.04 Storage Temperature: <0°C
Catalog Number:
(10352-854)
Supplier:
Bioss
Description:
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Supplier:
TCI America
Description:
CAS Number: 626-13-1
MDL Number: MFCD00059315 Molecular Formula: C14H15N Molecular Weight: 197.28 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 200 Melting point (°C): -12 Flash Point (°C): 110 Specific Gravity (20/20): 1.04
Supplier:
TCI America
Description:
CAS Number: 107-88-0
MDL Number: MFCD00004554 Molecular Formula: C4H10O2 Molecular Weight: 90.12 Purity/Analysis Method: >99.0% (GC) Form: Clear Liquid Boiling point (°C): 207 Flash Point (°C): 122 Specific Gravity (20/20): 1.01
Catalog Number:
(TCD0722-100ML)
Supplier:
TCI America
Description:
CAS Number: 68-12-2
MDL Number: MFCD00003284 Molecular Formula: C3H7NO Molecular Weight: 73.10 Purity/Analysis Method: >99.5% (GC) Form: Clear Liquid Boiling point (°C): 153 Melting point (°C): -61 Flash Point (°C): 60 Specific Gravity (20/20): 0.95
Supplier:
TCI America
Description:
(stabilized with MEHQ)
CAS Number: 376-84-1 Molecular Formula: C8H6F8O2 Molecular Weight: 286.12 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 84 Flash Point (°C): 72 Specific Gravity (20/20): 1.49 Storage Temperature: 0-10°C
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