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Ace+Method+Development+Kits
Supplier:
TCI America
Description:
CAS Number: 138372-67-5
MDL Number: MFCD03093214 Molecular Formula: C30H30N4O2 Molecular Weight: 478.60 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Melting point (°C): 241 Lambda max.: 292 nm (CH2Cl2)
Catalog Number:
(TCH0490-500ML)
Supplier:
TCI America
Description:
[for HPLC Solvent]
CAS Number: 110-54-3 MDL Number: MFCD00009520 Molecular Formula: C6H14 Molecular Weight: 86.18 Purity/Analysis Method: >96.0% (GC) Form: Clear Liquid Boiling point (°C): 68 Melting point (°C): -95 Flash Point (°C): -22 Specific Gravity (20/20): 0.66
Catalog Number:
(10098-332)
Supplier:
Prosci
Description:
Wnt1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta catenine. Mature human Wnt1 is a glycosylated protein containing 343 amino acid residues.
Supplier:
TCI America
Description:
CAS Number: 23357-46-2
MDL Number: MFCD00671629 Molecular Formula: C10H13N Molecular Weight: 147.22 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Color: Colorless Boiling point (°C): 70 Flash Point (°C): 110 Specific Gravity (20/20): 1.04 Specific rotation [a]20/D: -28 deg (C=2, MeOH)
Catalog Number:
(CA82021-582)
Supplier:
G-Biosciences
Description:
G-Biosciences' CytoScan™ LDH Cytotoxicity Assay is a colorimetric method of assaying cellular cytotoxicity and is an alternative to ⁵¹Cr release cytotoxicity assays
Supplier:
TCI America
Description:
CAS Number: 262-89-5
Molecular Formula: C16H12 Molecular Weight: 204.27 Purity/Analysis Method: >97.0% (GC) Form: Crystal Boiling point (°C): 130 Melting point (°C): 107 Lambda max.: 304 nm (CH2Cl2)Storage Temperature: 0-10°C
Catalog Number:
(TCD4247-5G)
Supplier:
TCI America
Description:
[for Biochemical Research]
CAS Number: 15178-76-4 MDL Number: MFCD00036912 Molecular Formula: C13H29NO3S Molecular Weight: 279.44 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Melting point (°C): 205
Catalog Number:
(10412-902)
Supplier:
Bioss
Description:
Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate and divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid (one too many or too few chromatids), the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers.
Catalog Number:
(10448-576)
Supplier:
Bioss
Description:
CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Catalog Number:
(10464-122)
Supplier:
Bioss
Description:
Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Catalog Number:
(76085-224)
Supplier:
Bioss
Description:
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
Supplier:
Yamato Scientific
Description:
The air-jacket technology of these incubators ensures even and efficient heat distribution throughout the chamber.
Supplier:
TCI America
Description:
CAS Number: 23735-43-5
MDL Number: MFCD00063234 Molecular Formula: C13H18O5S Molecular Weight: 286.34 Purity/Analysis Method: >98.0% (GC) Form: Crystal Flash Point (°C): 110 Freezing point (°C): 25 Specific rotation [a]20/D: 8 deg (C=2, DMF) Storage Temperature: 0-10°C
Catalog Number:
(TCA2097-5G)
Supplier:
TCI America
Description:
CAS Number: 1064-48-8
MDL Number: MFCD00004017 Molecular Formula: C22H16N6O9S2 Molecular Weight: 616.49 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Lambda max.: 618 nm (H2O)
Catalog Number:
(TCD4250-250MG)
Supplier:
TCI America
Description:
CAS Number: 4235-95-4
MDL Number: MFCD00135191 Molecular Formula: C44H84NO8P Molecular Weight: 786.13 Purity/Analysis Method: >97.0% (HPLC,T) Form: Crystal Specific rotation [a]20/D: 5 deg (C=0.5, CHCl3:MeOH=4:1) Storage Temperature: <0°C
Catalog Number:
(89417-706)
Supplier:
Prosci
Description:
ZIP13 Antibody: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
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