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Ace+Method+Development+Kits
Catalog Number:
(10431-272)
Supplier:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue.
Supplier:
TCI America
Description:
Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: H-Gly-Val-OH
Supplier:
TCI America
Description:
Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: H-Gly-Phe-OH
Catalog Number:
(N-1640.0005BA)
Supplier:
Bachem Americas
Description:
AC-VEID-CHO, a specific inhibitor of caspase-6 (Mch2).
Supplier:
Shenandoah Biotechnology
Description:
Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.
Catalog Number:
(CA45001-112)
Supplier:
Corning
Description:
MCDB 131 was originally developed by the researchers Knedler and Ham for the low-protein and serum free growth of human microvascular endothelial cells (HMVEC)
Catalog Number:
(10108-924)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10394-886)
Supplier:
Bioss
Description:
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Catalog Number:
(76119-256)
Supplier:
Bioss
Description:
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Supplier:
TCI America
Description:
CAS Number: 74844-91-0
MDL Number: MFCD00076981 Molecular Formula: C11H19NO5 Molecular Weight: 245.28 Purity/Analysis Method: >95.0% (GC) Form: Crystal Boiling point (°C): 132 Melting point (°C): 96 Specific rotation [a]20/D: -79 deg (C=1, MeOH)
Catalog Number:
(CAJT4274-1)
Supplier:
AVANTOR PERFORMANCE MATERIAL LLC
Description:
Sticks. Lot analysis reported on label.
Catalog Number:
(89366-320)
Supplier:
Genetex
Description:
Rabbit Polyclonal Antibody to RNF12
Catalog Number:
(10109-278)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(CA10145-970)
Supplier:
HARDY DIAGNOSTICS CA
Description:
CompactDry™ X-SA is a ready-to-use test method recommended for the isolation and enumeration of <i>Staphylococcus aureus</i> in raw materials, finished products, or on environmental surfaces pertaining to food and related industries.
Supplier:
Biotium
Description:
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(10670-942)
Supplier:
Bioss
Description:
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. In vivo, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes. Specifically, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, thus inducing transcription of the HoxD9 promoter. HoxD9 may be a multifunctional transcriptional regulator, as it contains different activation domains. Activation of HoxD9 depends on the structure of the target regulatory element, and results in differential cofactor interaction. The HoxD9 protein is expressed in the early stages of mouse joint development, primarily in the articular cartilage. HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, but not in that of normal mice, suggesting that HoxD9 may have a role in the pathology of arthritis. Furthermore, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), but not in osteoarthritis patients. The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, but is not expressed in the normal cervix and may thus play a role in tumorigenesis.
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