Ace+Method+Development+Kits
Catalog Number:
(10107-358)
Supplier:
Prosci
Description:
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21;q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Catalog Number:
(10081-684)
Supplier:
Proteintech
Description:
NUMB, also named as S171, plays a role in the determination of cell fates during development. It is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. The degradation of NUMB is induced in a proteasome-dependent manner by MDM2. Four transcript variants encoding different isoforms have been found for this gene. The antibody can bind to all these four isoforms P65, P66, P71 and P72, can’t recognize the NUMBL.
Catalog Number:
(CAPIPA5-13111)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with mouse, rat and zebrafish based on sequence homology. HAND2 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
Catalog Number:
(TCA0877-025ML)
Supplier:
TCI America
Description:
CAS Number: 2497-18-9
MDL Number: MFCD00009474 Molecular Formula: C8H14O2 Molecular Weight: 142.20 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 165 Flash Point (°C): 64 Specific Gravity (20/20): 0.90
Catalog Number:
(TCT3053-100MG)
Supplier:
TCI America
Description:
CAS Number: 80663-92-9
MDL Number: MFCD09835379 Molecular Formula: C36H44 Molecular Weight: 476.75 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Color: Slightly Pale Yellow Melting point (°C): 312 Lambda max.: 439 nm (DMSO)
Supplier:
TCI America
Description:
CAS Number: 98130-56-4
MDL Number: MFCD00070752 Molecular Formula: C6H3BrF2O Molecular Weight: 208.99 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 53 Flash Point (°C): 106 Specific Gravity (20/20): 1.85
Supplier:
TCI America
Description:
CAS Number: 364385-54-6
MDL Number: MFCD09952106 Molecular Formula: C11H22N2O2 Molecular Weight: 214.31 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Specific rotation [a]20/D: 5.0 deg (C=1, CH2Cl2) Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
CAS Number: 1996-30-1
MDL Number: MFCD00672934 Molecular Formula: C6H3BrClF Molecular Weight: 209.44 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 90 Flash Point (°C): 85 Specific Gravity (20/20): 1.74
Supplier:
TCI America
Description:
CAS Number: 2142-70-3
MDL Number: MFCD00094998 Molecular Formula: C8H7IO Molecular Weight: 246.05 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 144 Flash Point (°C): 103 Specific Gravity (20/20): 1.77
Supplier:
TCI America
Description:
CAS Number: 1760-24-3
MDL Number: MFCD00008173 Molecular Formula: C8H22N2O3Si Molecular Weight: 222.36 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 146 Flash Point (°C): 143 Specific Gravity (20/20): 1.03
Catalog Number:
(TCL0162-500G)
Supplier:
TCI America
Description:
CAS Number: 687-47-8
MDL Number: MFCD00004518 Molecular Formula: C5H10O3 Molecular Weight: 118.13 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 70 Flash Point (°C): 46 Specific Gravity (20/20): 1.04 Specific rotation [a]20/D: -10.8 deg (neat)
Supplier:
TCI America
Description:
CAS Number: 63131-29-3
MDL Number: MFCD00000355 Molecular Formula: C10H9FO3 Molecular Weight: 196.18 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 91 Flash Point (°C): 110 Specific Gravity (20/20): 1.24
Catalog Number:
(10461-968)
Supplier:
Bioss
Description:
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Catalog Number:
(10461-970)
Supplier:
Bioss
Description:
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Catalog Number:
(10451-018)
Supplier:
Bioss
Description:
The BMP15 protein is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The transforming growth factor beta superfamily includes large families of growth and differentiation factors. It is thought that BMP15 may be involved in oocyte maturation and follicular development as a homodimer, or by forming heterodimers with a related protein, Gdf9.
Supplier:
TCI America
Description:
CAS Number: 82956-11-4
MDL Number: MFCD00941430 Molecular Formula: C19H17N5O2 Molecular Weight: 539.58 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 258
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