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Ace+Method+Development+Kits
Catalog Number:
(76119-206)
Supplier:
Bioss
Description:
Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
Supplier:
TCI America
Description:
CAS Number: 87-24-1
MDL Number: MFCD00009112 Molecular Formula: C10H12O2 Molecular Weight: 164.20 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 227 Flash Point (°C): 91 Specific Gravity (20/20): 1.04
Supplier:
TCI America
Description:
CAS Number: 569-61-9
MDL Number: MFCD00001657
Molecular Formula: C19H17N3
Molecular Weight: 323.82
Purity/Analysis Method: <gt/>95.0% (HPLC)
Form: Crystal
Melting point (°C): 270
Lambda max.: 539 nm (EtOH)
Supplier:
TCI America
Description:
CAS Number: 114214-69-6
MDL Number: MFCD02179040 Molecular Formula: C10H19NO3 Molecular Weight: 201.27 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 291 Specific Gravity (20/20): 1.06
Catalog Number:
(TCD0612-5G)
Supplier:
TCI America
Description:
CAS Number: 18835-59-1
MDL Number: MFCD00016542 Molecular Formula: C9H9I2NO3 Molecular Weight: 432.98 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 213 Specific rotation [a]20/D: 1.2 deg (C=5, 1mol/L HCl)
Supplier:
TCI America
Description:
CAS Number: 71617-10-2
MDL Number: MFCD00583856 Molecular Formula: C15H20O3 Molecular Weight: 248.32 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 158 Specific Gravity (20/20): 1.04
Catalog Number:
(TCM2030-5G)
Supplier:
TCI America
Description:
CAS Number: 26131-32-8
MDL Number: MFCD00054723 Molecular Formula: C10H3F17O4 Molecular Weight: 510.10 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 155 Specific Gravity (20/20): 1.66
Supplier:
TCI America
Description:
[Catalyst for Oxidation]
CAS Number: 14691-89-5 MDL Number: MFCD00043593 Molecular Formula: C11H21N2O2 Molecular Weight: 213.30 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 143 Flash Point (°C): 198
Supplier:
TCI America
Description:
CAS Number: 41556-26-7
MDL Number: MFCD00134706 Molecular Formula: C30H56N2O4 Molecular Weight: 508.79 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 222 Specific Gravity (20/20): 1.00
Catalog Number:
(TCI0795-100MG)
Supplier:
TCI America
Description:
CAS Number: 131833-97-1
MDL Number: MFCD07368371 Molecular Formula: C17H30N2O2 Molecular Weight: 294.44 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 90 Specific rotation [a]20/D: 119 deg (C=1, CHCl3)
Catalog Number:
(89416-162)
Supplier:
Prosci
Description:
Blimp-1 Antibody: Blimp-1 was initially identified as a zinc finger-containing protein that drives the maturation of B lymphocytes into immunoglobulin-secreting cells. Together with X-box-binding protein 1 (XBP1), Blimp-1 is induced upon terminal differentiation of plasma cells. The transcriptional repressor activity of Blimp-1 has also been found to regulate T cell homeostasis and function, possibly by suppressing the expression of the cytokines IL-2 and interferon-gamma during T cell development. More recent experiments have suggested that Blimp-1 also plays a major role in the formation of primordial germ cells (PGC) in developing mammalian embryos. In these experiments, Blimp-1-deficient mutant mouse embryos form a cluster of PGC-like cells which fail to show the expected migration, proliferation, and repression of homeobox genes that normally accompany specification of primordial germ cells. Blimp-1 exists as at least two different isoforms.
Catalog Number:
(89415-474)
Supplier:
Prosci
Description:
Noxa Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA. A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins. Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins. X-ray irradiation increased p53-dependent Noxa mRNA and protein levels. Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9. Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53. Noxa and PUMA may represent direct mediators of p53-induced apoptosis. Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.
Catalog Number:
(10347-636)
Supplier:
Bioss
Description:
Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.
Supplier:
Tonbo Biosciences
Description:
The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Catalog Number:
(CAJT0596-R)
Supplier:
AVANTOR PERFORMANCE MATERIAL LLC
Description:
Crystals. Lot analysis on label.
Supplier:
TCI America
Description:
CAS Number: 112-73-2
MDL Number: MFCD00009459 Molecular Formula: C12H26O3 Molecular Weight: 218.34 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 255 Melting point (°C): -60 Flash Point (°C): 122 Specific Gravity (20/20): 0.88
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