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Ace+Method+Development+Kits
Catalog Number:
(89360-126)
Supplier:
Genetex
Description:
WNT4 is a ligand for members of the frizzled family of seven transmembrane receptors and a probable developmental protein. It may be a signalling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters. Overexpression may be associated with abnormal proliferation in human breast tissue.
Catalog Number:
(10088-152)
Supplier:
Proteintech
Description:
Lymphoid-specific helicase(HELLS) ia a member of the SNF2 family of chromatin remodeling proteins that is required for development and survival. It's required for de novo or maintenance DNA methylation, which mediated the silencing of the imprinted CDKN1C gene. Also it involved in formation and organization of heterochromatin that regulate transcription and mitosis.
Catalog Number:
(10109-166)
Supplier:
Prosci
Description:
As an immediate-early protein, NOV is likely to play a role in cell growth regulation.
Supplier:
Chemplex
Description:
Vented Snap-On Cap equalizes pressure differentials within the Cell and sample chamber to maintain a taut thin-film sample support plane.
Catalog Number:
(10798-146)
Supplier:
Prosci
Description:
Receptor tyrosine-protein kinase erbB-4 (ErbB4), also known as Her4, is a single-pass type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors. ErbB4 is expressed in normal skeletal muscle, heart, pituitary, brain and several breast carcinomas. ERBB4 contains multiple furin-like cysteine rich domains, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins-2 and -3, heparin-binding EGF-like growth factor and betacellulin. Ligand binding induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. ErbB4 appears to play important roles in neuronal development, development of the heart and cancer. ERBB4 has been shown to interact with: DLG4, NRG1, STAT5A, and YAP1. Mutations in this gene have been associated with cancer. Other single-nucleotide polymorphisms and a risk haplotype have been linked to schizophrenia.
Supplier:
GLOBAL LIFE SCIENCES SOLUTIONS CA
Description:
HyClone SFMTransfx-293 is a serum-free, animal derived component-free medium designed to support the growth of HEK 293 cultures and promote transfection using lipofection or similar methods. Manufactured according to cGMP guidelines.
Catalog Number:
(CAPIPA5-18568)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with canine, mouse and rat based on sequence homology. The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I , and age-related macular degeneration type 3 .
Catalog Number:
(102867-634)
Supplier:
R&D Systems
Description:
The Recombinant Mouse Glycoprotein V/CD42d Protein from R&D Systems is derived from NS0. The Recombinant Mouse Glycoprotein V/CD42d Protein has been validated for the following applications: Bioactivity.
Catalog Number:
(10093-138)
Supplier:
Proteintech
Description:
RAB18 is a member of a family of Ras-related small GTPases. RAB18 plays a role in apical endocytosis/recycling, and may be implicated in transport between the plasma membrane and early endosomes. It also plays a key role in eye and brain development and neurodegeneration. Defects in RAB18 are associated with Warburg micro syndrome type 3.
Catalog Number:
(10088-146)
Supplier:
Proteintech
Description:
HECTD1 (E3 ubiquitin-protein ligase), which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates,may be required for development of the head mesenchyme and neural tube closure.It is also involved in sporadic Parkinson’s disease.This protein is specific to HECTD1.
Catalog Number:
(10106-328)
Supplier:
Prosci
Description:
Located on chromosome 1, this gene encodes for the DMRT-like family B with proline-rich C-terminal, 1 protein.
Catalog Number:
(10090-778)
Supplier:
Proteintech
Description:
MYPN is a component of the sarcomere that tethers nebulin in skeletal muscle and nebulette in cardiac muscle to alpha-actinin at the Z lines (from OMIM). Myopalladin and palladin share C-terminal fragment in sequence. While myopalladin are most abundant in skeletal and cardiac muscle, palladin is ubiquitously expressed in the organs of developing vertebrates. This antibody is specific to myopalladin.
Supplier:
Biotium
Description:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(89351-650)
Supplier:
Genetex
Description:
Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors, which are essential for muscle development. Transfection of myogenin into multipotential mesodermal cells have been shown to convert the mesodermal cells to myoblasts. Expression of myogenin is restricted to cells of skeletal muscle origin. It is therefore a useful marker for tumors of the muscle lineage, being strongly expressed in alveolar rhabdomyosarcomas.
Supplier:
Ward's Science
Description:
CAS Number: 1336-21-6
Formula: NH4OH Density: 0.900 g/mL Boiling and Freezing Point: 36°C, -77°C Synonyms: Ammonium Hydroxide Water Solution Shelf Life: 36 Months
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