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Ace+Method+Development+Kits
Catalog Number:
(10470-858)
Supplier:
Bioss
Description:
May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.Tissue specificity:Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas.
Catalog Number:
(89361-198)
Supplier:
Genetex
Description:
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Catalog Number:
(10232-136)
Supplier:
Bioss
Description:
Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
Catalog Number:
(10103-828)
Supplier:
Prosci
Description:
SETD3 contains 1 SET domain. The function of the SETD3 protein remains unknown.
Catalog Number:
(10105-376)
Supplier:
Prosci
Description:
Vasculin is a novel vascular protein differentially expressed in human atherogenesis
Catalog Number:
(89146-090)
Supplier:
Enzo Life Sciences
Description:
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging and neurodegenerative conditions, such as Alzheimer's disease. 8OHdG has become increasing popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA. Biomonitoring in humans has demonstrated that 8OHdG can be excreted in the urine and that a significant increase is caused by exposure to tobacco smoke and ionizing radiation. Because 8OHdG is so well correlated with oxidative stress and damage to DNA, which leads to degenerative disease states, the development of an antibody that can be used to study DNA damage has numerous applications. In addition to the direct study of DNA damage within cells, this antibody has applications in the development of immunoassays that can monitor 8OHdG excretion in the urine and serve as a biomarker of oxidative stress. Industrial uses may extend to the dietary supplement manufacturers, who could benefit from an immunoassay that could be used to test the effectiveness of antioxidants and other nutraceuticals.
Catalog Number:
(10109-198)
Supplier:
Prosci
Description:
As a Na/PO4 cotransporter, SLC17A4 may be important to the regulation of Li transport and its therapeutic effects.
Catalog Number:
(TCE0667-1G)
Supplier:
TCI America
Description:
CAS Number: 346656-34-6
Molecular Formula: C14H19BO4 Molecular Weight: 262.11 Purity/Analysis Method: >98.0% (T) Form: Clear Liquid Specific Gravity (20/20): 1.09 Storage Temperature: 0-10°C
Catalog Number:
(CA10065-278)
Supplier:
LONZA PHARMA - BIOSCIENCE CA
Description:
Clonetics® AGM® Astrocyte Growth Medium has been developed to support the growth of primary human astrocytes.
Supplier:
Ace Glass
Description:
These mini adapters are suitable for most vacuum work.
Catalog Number:
(CAPIPA5-18058)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, mouse and rat based on sequence homology. KLF4 (Kruppel-like factor 4 (gut)) is a transcription factor that can act both as an activator and as a repressor. KLF4 binds to the 5'-CACCC-3' core sequence, and binds to the promoter region of its own gene and it can activate its own transcription. It regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. It is also involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Diseases associated with KLF4 include skin sequamous cell carcinoma and familial adenomatous polyposis.
Catalog Number:
(10427-990)
Supplier:
Bioss
Description:
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Catalog Number:
(10400-424)
Supplier:
Bioss
Description:
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Catalog Number:
(10427-992)
Supplier:
Bioss
Description:
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Supplier:
Bachem Americas
Description:
See also Boc-Lys(Ac)-AMC (I-1875) and Boc-Lys(Tfa)-AMC (I-1985).
Catalog Number:
(10101-008)
Supplier:
Prosci
Description:
DMTF1 binds specifically to the nonamer DNA consensus sequences CCCG (G/T)ATGT to activate transcription.
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