Ace+Method+Development+Kits
Supplier:
Biotium
Description:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number:
(75792-986)
Supplier:
Prosci
Description:
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Catalog Number:
(10478-480)
Supplier:
Bioss
Description:
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.Tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Supplier:
Shenandoah Biotechnology
Description:
Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
Supplier:
TCI America
Description:
CAS Number: 2566-97-4
MDL Number: MFCD00069997 Molecular Formula: C19H34O2 Molecular Weight: 294.48 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 152 Specific Gravity (20/20): 0.88 Storage Temperature: <0°C
Catalog Number:
(89363-096)
Supplier:
Genetex
Description:
Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.
Catalog Number:
(10764-198)
Supplier:
Prosci
Description:
The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein. CD81 is expressed broadly on B cells, T cells, NK cells, dendritic cells, fibroblasts, and endothelial cells. It plays a role in T cell development and is involved in B and T cell adhesion. The Eat-2 antibody is also reported to cross-react with the rat CD81 antigen.
Supplier:
TCI America
Description:
CAS Number: 762240-92-6
MDL Number: MFCD09817638 Molecular Formula: C6H7F3N4 Molecular Weight: 228.60 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Color: White Melting point (°C): 264
Catalog Number:
(103009-026)
Supplier:
Anaspec Inc
Description:
This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
Sequence:GAHWQFNALTVRGGGS-K(Biotin) MW:2012.2 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(76099-692)
Supplier:
Bioss
Description:
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
Catalog Number:
(TCB4083-5G)
Supplier:
TCI America
Description:
CAS Number: 53100-44-0
MDL Number: MFCD00672316 Molecular Formula: C10H15NO5 Molecular Weight: 229.23 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 119 Specific rotation [a]20/D: -34 deg (C=1, CHCl3) Storage Temperature: 0-10°C
Supplier:
TCI America
Description:
CAS Number: 41051-80-3
MDL Number: MFCD00039882 Molecular Formula: C10H25NO3Si Molecular Weight: 235.40 Purity/Analysis Method: >97.0% (GC,T) Form: Clear Liquid Boiling point (°C): 120 Flash Point (°C): 100 Specific Gravity (20/20): 0.94
Catalog Number:
(CA-FX0420-6)
Supplier:
MilliporeSigma
Description:
Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs
Supplier:
Kinematica
Description:
Standard dispersing generators come with the EC (EasyClean) design and rotor/stator geometries with two, four or six teeth rows. This is all you need for popular applications in the preparation of samples, formulation development and small-scale production. Dispersing generators are made from high-alloy stainless steel 316L, electropolished, Ra≤1.6 μm as standard.
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Supplier:
Ace Glass
Description:
These fritted discs are used with Ace Glass membrane filtration apparatus.
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