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Ace+Method+Development+Kits
Catalog Number:
(10751-236)
Supplier:
Prosci
Description:
VPS39 Antibody: VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.
Catalog Number:
(10483-488)
Supplier:
Bioss
Description:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
Supplier:
TCI America
Description:
CAS Number: 1117-86-8
MDL Number: MFCD00010738 Molecular Formula: C8H18O2 Molecular Weight: 146.23 Purity/Analysis Method: >96.0% (GC) Form: Crystal Flash Point (°C): 110 Freezing point (°C): 26
Catalog Number:
(89141-382)
Supplier:
Enzo Life Sciences
Description:
Beclin-1 is a coiled-coil Bcl-2-interacting protein that functions in autophagy, the process of bulk degradation of cellular proteins. Beclin-1 is homologous to the yeast autophagy gene apg6, and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors. Bcl-2 can inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as both an anti-autophagic and anti-apoptotic protein.
Catalog Number:
(76119-534)
Supplier:
Bioss
Description:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
Catalog Number:
(10096-314)
Supplier:
Proteintech
Description:
Tripartite motif-containing 14(TRIM14) belongs to the TRIM protein family that contains 3 zinc-binding domains, a RING, a B-box type1 and a B-box type2 and plays key roles in cellular proliferation, differentiation, development, transformation, and immune response mechanisms . TRIM4 inhibits the transcriptional activity of SPI1 in a dose-dependent manner. It may participate in the early stages of differentiation of embryonic stem cells, leading to the formation of embryoid bodies.
Catalog Number:
(10096-588)
Supplier:
Proteintech
Description:
The ubiquinol cytochrome c reductase UQCRFS1 is a key subunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain. The UQCRFS1 gene encode a 30 kDa protein with a transit peptide and it appears to be involved in development of more aggressive phenotype of breast cancer. UQCRFS1 is also named as RISP, complex III subunit 5, cytochrome b-c1 complex subunit 5 and rieske iron-sulfur protein. This antibody is specific to UQCRFS1.
Supplier:
Tonbo Biosciences
Description:
The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.
Catalog Number:
(10111-758)
Supplier:
Prosci
Description:
ZBTB10 contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. ZBTB10 may be involved in transcriptional regulation.
Catalog Number:
(103007-584)
Supplier:
Anaspec Inc
Description:
This is amino acids 1 to 12 fragment of the beta-amyloid peptide. This N-terminal sequence was used to develop the antibody BR88. An antiserum directed against this peptide stained numerous tangle-bearing cells and bodies, as well as the neuritic component of plaques and neuropil threads. It stained a large number of pyramid cells.
Sequence: DAEFRHDSGYEV Molecular Weight: 1424.5 Da % Peak Area by HPLC: ≥95 Peptide Content: ≥ 60% Storage condition: -20°C
Catalog Number:
(CA89006-808)
Supplier:
3M
Description:
3M™ E-A-Rsoft™ metal detectable earplugs were specially developed for food processing and other industries where it is critical to keep earplugs from contaminating products and processes.
Catalog Number:
(10452-554)
Supplier:
Bioss
Description:
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.
Supplier:
Ricca Chemical
Description:
Methanol absolute ACS
Catalog Number:
(10355-648)
Supplier:
Bioss
Description:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
Catalog Number:
(CA610-4341)
Supplier:
Rockland Immunochemical
Description:
Anti-Mouse IgG2a heavy chain antibody is suitable for highly specific immunological methods requiring extremely low background levels, lot-to-lot consistency, high titer and specificity.
Catalog Number:
(10082-834)
Supplier:
Proteintech
Description:
Anti-Müllerian hormone (AMH), also called Müllerian-inhibiting substance (MIS), is a hormone that is best known for its production by fetal testes in mammals and as the inhibitor of Müllerian duct development in males. AMH is also expressed in granulosa cells of preantral and small antral follicles in the ovary. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve.This antibody is specific to AMH.
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