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Ace+Method+Development+Kits
Catalog Number:
(10108-410)
Supplier:
Prosci
Description:
ADAD2 belongs to the ADAD family, and contains 1 A to I editase domain and 1 DRBM (double-stranded RNA-binding) domain. The exact functions of ADAD2 remain unknown.
Catalog Number:
(10111-334)
Supplier:
Prosci
Description:
EVX1 is a member of the vertebrate eve-related homeo box family. This protein acts as a transcriptional repressor. A similar protein in mice is critical for early embryogenesis.
Catalog Number:
(10108-598)
Supplier:
Prosci
Description:
LDB3 may function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
Catalog Number:
(10108-386)
Supplier:
Prosci
Description:
LARP1 belongs to the LARP family and it contains 1 HTH La-type RNA-binding domain. The exact function of LARP1 remains unknown.
Catalog Number:
(76084-374)
Supplier:
Bioss
Description:
PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
Catalog Number:
(CA-LX0350-5)
Catalog Number:
(76081-492)
Supplier:
Bioss
Description:
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters.
Supplier:
DWK Life Sciences (KIMBLE)
Description:
Wheaton manufactures a new line of high density cell culture membrane flasks for antibody and protein production. CELLine works well with secreting cell lines such as Hybridoma, CHO, NS0, SF, HEK, and BHK cells. Conventional in vivo or in vitro cell culture methods can be laborious, low density and require significant purification. CELLine dual compartment flasks separate the cell compartment from the bulk media compartment with a 10 kD MWCO dialysis membrane. This allows for longer run times, high density cultures, and a super concentrated harvest. The CELLine flasks were designed to address three areas of limitation:
Supplier:
Ace Glass
Description:
Large, borosilicate glass vessel coated with Ace Instatherm®
Catalog Number:
(102092-152)
Supplier:
Electron Microscopy Sciences
Description:
Specially developed to provide compatibility with National Diagnostic clearing agents, HistoClear II. Omnimount™ combined outstanding optical characteristics with low fluororescence and exceptional durability.
Catalog Number:
(10104-534)
Supplier:
Prosci
Description:
ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is involved in ITPR1 degradation by the ERAD pathway.
Catalog Number:
(10102-762)
Supplier:
Prosci
Description:
WDSUB1 contains 1 SAM (sterile alpha motif) domain, 1 U-box domain and 7 WD repeats. The function of WDSUB1 remains unknown.
Supplier:
MilliporeSigma
Description:
Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs
Catalog Number:
(10108-020)
Supplier:
Prosci
Description:
EIF4G3 is probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. It is thought to be a functional homolog of EIF4G1.
Catalog Number:
(10111-320)
Supplier:
Prosci
Description:
The TFEB gene fuses with an intronless gene in renal tumors harboring the t (6;11) (p21;q13) chromosome translocation. It encodes a protein that is a highly sensitive and specific diagnostic marker for renal neoplasms.
Catalog Number:
(10108-232)
Supplier:
Prosci
Description:
C19orf24 is a novel human non-classical secreted protein which is encoded by the hypothetical gene C19orf24 (chromosome 19 open reading frame 24). The exact function of C19orf24 remains unknown.
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