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Ace+Method+Development+Kits
Catalog Number:
(10101-208)
Supplier:
Prosci
Description:
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.
Supplier:
Tonbo Biosciences
Description:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Catalog Number:
(10370-192)
Supplier:
Bioss
Description:
Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.
Catalog Number:
(10748-560)
Supplier:
Prosci
Description:
SOCS1 Antibody: The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines. SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase. SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome. It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.
Catalog Number:
(10107-010)
Supplier:
Prosci
Description:
LMX1B is essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Defects in LMX1B are the cause of nail-patella syndrome (NPS) also knowan as Onychoosteodysplasia.
Catalog Number:
(10103-928)
Supplier:
Prosci
Description:
PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFDN6 binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Catalog Number:
(10110-416)
Supplier:
Prosci
Description:
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template.
Catalog Number:
(89156-654)
Supplier:
Enzo Life Sciences
Description:
Highly specific substrate for the caspase-like peptidic activity of the 20S proteasome.
Catalog Number:
(89051-340)
Supplier:
Ace Glass
Description:
The top side arm of this Claisen adapter has a #7 Ace-Thred for use with a nylon bushing for an adjustable length thermometer.
Supplier:
Bachem Americas
Description:
These short peptides act as angiotensin I-converting enzyme (ACE) inhibitors. See also Phe-Tyr (G-2955) and the subfamilies 'Bradykinin-Potentiating Peptide (BPP)' and 'Angiotensin I-Converting Enzyme (ACE, ACE2) Inhibitors'.
Supplier:
Ace Glass
Description:
This adapter is available in both "Midi" and "Maxi" formats
Supplier:
MilliporeSigma
Description:
SupraSolv® MS is dedicated for use in gas chromatography coupled with mass spectrometric detection. SupraSolv® solvents offer the largest specified retention time range, a clear baseline and a minimal signal-to-noise ratio leading to reliable and reproducible analysis results. This method is used e. g. for the analysis of dioxins and furans (PCDD/PCDF) in food and water samples or for the determination of PAH (polycyclic aromatic hydrocarbons) in food.
Catalog Number:
(10102-782)
Supplier:
Prosci
Description:
RNF207 contains 1 B box-type zinc finger and 1 RING-type zinc finger. The function of the RNF207 protein remains unknown.
Catalog Number:
(10101-770)
Supplier:
Prosci
Description:
CCT8L2 belongs to the TCP-1 chaperonin family. It possible molecular chaperone and assists the folding of proteins upon ATP hydrolysis.
Catalog Number:
(10106-794)
Supplier:
Prosci
Description:
Mouse Ces6 is a member of carboxylesterases family. Carboxylesterases are enzymes that catalyze the hydrolysis of a wide range of ester-containing endogenous and xenobiotic compounds.
Catalog Number:
(10099-812)
Supplier:
Prosci
Description:
SLC23A3 is a multi-pass membrane protein. It belongs to the xanthine/uracil permease family, SLC23A subfamily. The exact function of SLC23A3 remains unknown.
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