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Ace+Method+Development+Kits
Catalog Number:
(89415-518)
Supplier:
Prosci
Description:
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kappa B. CARD9 is an upstream activator of BCL-10 and NF-kappa B signaling.
Supplier:
Ace Glass
Description:
PTFE packing for use in stuffing boxes
Catalog Number:
(10101-868)
Supplier:
Prosci
Description:
ZNF778 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 19 C2H2-type zinc fingers and 1 KRAB domain. ZNF778 may be involved in transcriptional regulation.
Catalog Number:
(10110-472)
Supplier:
Prosci
Description:
ZFP92 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 8 C2H2-type zinc fingers and 1 KRAB domain. ZFP92 may be involved in transcriptional regulation.
Catalog Number:
(10782-654)
Supplier:
Biosensis
Description:
NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
Catalog Number:
(TCD3983-100MG)
Supplier:
TCI America
Description:
CAS Number: 903571-02-8
MDL Number: MFCD10566989 Molecular Formula: C21H22ClN3O Molecular Weight: 367.88 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 219 Specific rotation [a]20/D: 158 deg (C=1, CHCl3)
Catalog Number:
(89084-674)
Supplier:
Ace Glass
Description:
This single-post stand is designed for 30.5 cm (12") and 45.7 cm (18") height chromatography columns
Catalog Number:
(10110-632)
Supplier:
Prosci
Description:
ZNF486 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 2 C2H2-type zinc fingers and 1 KRAB domain. ZNF486 may be involved in transcriptional regulation.
Catalog Number:
(10110-626)
Supplier:
Prosci
Description:
TRIM48 belongs to the TRIM/RBCC family. It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. The exact function of TRIM48 remains unknown.
Catalog Number:
(10814-106)
Supplier:
Prosci
Description:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.
Catalog Number:
(10452-720)
Supplier:
Bioss
Description:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Catalog Number:
(89360-824)
Supplier:
Genetex
Description:
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted ""Glycine-X-Y"" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. This preparation results in a native conformation of the protein.
Supplier:
Ace Glass
Description:
Cylindrical vessel with 2 mm bore PTFE stopcock at either end, and porosity C (25–50 µm) fritted disc top and bottom
Supplier:
Tonbo Biosciences
Description:
The Hit8a antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Supplier:
Tonbo Biosciences
Description:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
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