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Catalog Number:
(10782-654)
Supplier:
Biosensis
Description:
NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
Catalog Number:
(10105-808)
Supplier:
Prosci
Description:
SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Supplier:
TCI America
Description:
CAS Number: 62965-35-9
MDL Number: MFCD00065574 Molecular Formula: C11H21NO4 Molecular Weight: 231.29 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 119 Specific rotation [a]20/D: -4 deg (C=1, AcOH)
Supplier:
Ace Glass
Description:
65MM WRENCH.
Supplier:
TCI America
Description:
CAS Number: 665-66-7
MDL Number: MFCD00074723 Molecular Formula: C10H17N Molecular Weight: 187.71 Purity/Analysis Method: >99.0% (T) Form: Crystal Melting point (°C): 360
Catalog Number:
(89428-016)
Supplier:
Ace Glass
Description:
This borosilicate glass vacuum trap is supplied with a no
Catalog Number:
(10418-652)
Supplier:
Bioss
Description:
MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
Catalog Number:
(10664-086)
Supplier:
Bioss
Description:
The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively.
Catalog Number:
(10748-958)
Supplier:
Prosci
Description:
Mitofusin 2 (MFN2) and the related protein MFN1 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN2 is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. MFN2 has two key domains: a coiled coil region that mediates MFN2 binding and a GTPase domain that likely plays a role in fusion. Both domains are essential for embryonic development and may play a role in the pathobiology of obesity. Overexpression of MFN2 causes mitochondrial dysfunction and cell death.
Catalog Number:
(10455-570)
Supplier:
Bioss
Description:
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Catalog Number:
(TCU0085-1G)
Supplier:
TCI America
Description:
CAS Number: 34661-75-1
MDL Number: MFCD00133908 Molecular Formula: C20H29N5O3 Molecular Weight: 387.48 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Color: White Melting point (°C): 159 Lambda max.: 268 nm (MeOH)
Catalog Number:
(TCC2520-250MG)
Supplier:
TCI America
Description:
CAS Number: 117048-59-6
MDL Number: MFCD03453309 Molecular Formula: C18H20O5 Molecular Weight: 316.35 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 83 Storage Temperature: <0°C
Supplier:
TCI America
Description:
CAS Number: 4358-87-6
MDL Number: MFCD00004493 Molecular Formula: C9H10O3 Molecular Weight: 166.18 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 250 Melting point (°C): 56
Supplier:
TCI America
Description:
CAS Number: 7382-30-1
MDL Number: MFCD23703159 Molecular Formula: C11H24O4 Molecular Weight: 220.31 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Color: Colorless Melting point (°C): -34 Specific Gravity (20/20): 0.94
Catalog Number:
(10666-384)
Supplier:
Bioss
Description:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The FAM135B gene product has been provisionally designated FAM135B pending further characterization.
Supplier:
TCI America
Description:
CAS Number: 147539-41-1
MDL Number: MFCD02259411 Molecular Formula: C11H22N2O2 Molecular Weight: 214.31 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Flash Point (°C): 110 Specific Gravity (20/20): 1.00 Storage Temperature: 0-10°C
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