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Ace+Method+Development+Kits
Catalog Number:
(76101-458)
Supplier:
Bioss
Description:
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Catalog Number:
(89064-064)
Supplier:
Ace Glass
Description:
REPLACEMENT CAPS, 20ML SIZE, OPEN-TOP PTFE-FACED, CS/200, w240518.
Catalog Number:
(10071-870)
Supplier:
Prosci
Description:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-κ-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Catalog Number:
(CAPIPA5-18408)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
Catalog Number:
(10110-718)
Supplier:
Prosci
Description:
DYNC1I1 belongs to the dynein intermediate chain family. It contains 7 WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Catalog Number:
(10105-112)
Supplier:
Prosci
Description:
AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
Catalog Number:
(10104-768)
Supplier:
Prosci
Description:
LYL1 contains 1 basic helix-loop-helix (bHLH) domain. A chromosomal aberration, translocation t (7;19) (q35;p13) with TCRB, involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL).
Catalog Number:
(10102-582)
Supplier:
Prosci
Description:
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling.
Supplier:
Tonbo Biosciences
Description:
The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
Supplier:
TCI America
Description:
CAS Number: 2198-61-0
MDL Number: MFCD00027280 Molecular Formula: C11H22O2 Molecular Weight: 186.30 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 98 Flash Point (°C): 88 Specific Gravity (20/20): 0.86
Supplier:
Ace Glass
Description:
Multi-purpose clamp ideal for holding large cylindrical glassware and similar objects
Supplier:
TCI America
Description:
CAS Number: 124655-17-0
MDL Number: MFCD00065575 Molecular Formula: C11H21NO4 Molecular Weight: 231.29 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 120 Specific rotation [a]20/D: 5 deg (C=1, AcOH)
Catalog Number:
(10108-082)
Supplier:
Prosci
Description:
THOC1 is part of the TREX (transcription/export) complex, which includes TEX1, THO2, ALY, and UAP56.HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 606390).
Catalog Number:
(10110-748)
Supplier:
Prosci
Description:
SPON2 is a cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. It is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.
Catalog Number:
(10108-200)
Supplier:
Prosci
Description:
PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
Supplier:
Restek
Description:
The general-purpose Restek C18 is a conventional monomeric octadecylsilane column suitable for analyses of a wide range of compounds from acidic through slightly basic.
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