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Ace+Method+Development+Kits
Catalog Number:
(10089-978)
Supplier:
Proteintech
Description:
MARCKS is a member of MARCKS family of PKC substrate and it is also a widely accepted indicator of PKC activation. It shows a ubiquitous tissue distribution. The calculated molecular weight of MARCKS is 39 kDa and its apparent molecular weights were found at 68 kDa to 90 kDa in different species. This protein is a known to regulated cytoskeleton remodeling and membrane recycling. The anti-MARCKS antibody is raised against purified MARCKS protein from mouse brain using a method similar to that previously reported for MacMARCKS
Catalog Number:
(10081-130)
Supplier:
Proteintech
Description:
STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This antibody is specific to STAT5B. It has no cross reaction to STAT5A.
Catalog Number:
(10434-382)
Supplier:
Bioss
Description:
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Catalog Number:
(10764-376)
Supplier:
Prosci
Description:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
Supplier:
Ace Glass
Description:
Microscale sublimation adapter with vertically adjustable condenser tube that allows use with 3, 5, and 10 mL microscale vessels.
Supplier:
Ace Glass
Description:
These heavy wall glass reactors are available with a 60mm (2.4"), 100mm (4"), or 150mm (6") diameter Duran style flange with O-Ring groove at top
Catalog Number:
(103008-644)
Supplier:
Anaspec Inc
Description:
This peptide is histone H4 amino acid residues 1 to 21. It is acetylated at the N-terminus, and trimethylated at Lys-12 with a C-terminal GG linker, followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:Ac-SGRGKGGKGLG-K(Me3)-GGAKRHRKV-GGK(Biotin) MW:2644.1 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10104-468)
Supplier:
Prosci
Description:
The function remains unknown.
Supplier:
PeproTech, Inc.
Description:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Rat IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
Catalog Number:
(89084-714)
Supplier:
Ace Glass
Description:
These strong alloy end-to-end connectors permit end-to-end joining of rods
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00009520
Beilstein Registry No.: 1730733
Notes: Meets ACS spectrophotometric requirements. Filtered through 0.2µ filters
Catalog Number:
(103008-636)
Supplier:
Anaspec Inc
Description:
This peptide is histone H4 amino acid residues 1 to 21. It is monomethylated at Arg3, with an acetylated N-terminus and C-terminal GG linker, followed by a biotinylated Lys. Methylation of histone H4 at Arg3 is an important step in transcriptional activation and allows for subsequent acetylation of H4 tails by p300. Provided at >90% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.'
Sequence:Ac-SG-R(Me1)-GKGGKGLGKGGAKRHRKV-GGK(Biotin) MW:2616.1 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(14003-068)
Supplier:
Sper Scientific
Description:
For use with thermometers in 14003-070 series.
Supplier:
Ace Glass
Description:
Compact, time-proportional digital temperature controller with two 120vac front outlets
Supplier:
Ace Glass
Description:
Positive, two-piece anodized clamp for securing reaction flasks with flat-style flanges
Catalog Number:
(76118-024)
Supplier:
Bioss
Description:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
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