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Ace+Method+Development+Kits
Supplier:
MilliporeSigma
Description:
Hydrogen peroxide (Perhydrol), Grade:ACS,ISO, Purity:30%, Synonyms:Perhydrol, Application:for analysis EMSURE
Catalog Number:
(10085-216)
Supplier:
Proteintech
Description:
Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors . In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina . Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms .
Catalog Number:
(CAPIPA5-17998)
Supplier:
Thermo Scientific
Description:
This product is expected to recognize both reported isoforms (NP_003022. 3; NP_001006611. 1). This antibody is predicted to react with bovine and canine based on sequence homology. This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Supplier:
Ace Glass
Description:
Multipurpose, borosilicate glass vial designed for storage and shipment of small volumes.
Catalog Number:
(77439-908)
Supplier:
Bioss
Description:
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
Catalog Number:
(10111-640)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10111-616)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10111-586)
Supplier:
Prosci
Description:
The specific function of this protein remains unknown.
Catalog Number:
(10111-358)
Supplier:
Prosci
Description:
Zinc finger protein 174.
Supplier:
Ace Glass
Description:
Tygon S3™ E-3603 phthalate-free vacuum tubing will withstand full vacuum at room temperature.
Supplier:
Ace Glass
Description:
Replacement borosilicate glass components for Buchi® R-220, R-220EX, and R-220SE rotary evaporators
Catalog Number:
(10109-114)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10109-328)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10075-650)
Supplier:
Prosci
Description:
Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
Catalog Number:
(10478-944)
Supplier:
Bioss
Description:
FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Catalog Number:
(10419-266)
Supplier:
Bioss
Description:
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
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