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Ace+Method+Development+Kits
Catalog Number:
(10434-396)
Supplier:
Bioss
Description:
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Catalog Number:
(89415-518)
Supplier:
Prosci
Description:
CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kappa B. CARD9 is an upstream activator of BCL-10 and NF-kappa B signaling.
Catalog Number:
(10448-210)
Supplier:
Bioss
Description:
CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.
Catalog Number:
(10488-094)
Supplier:
Bioss
Description:
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
Catalog Number:
(10107-762)
Supplier:
Prosci
Description:
PRMT5 methylates specific arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3 to monomethylarginine and to symmetrical dimethylarginines (sDMAs). It methylates SUPT5H. PRMT5 plays a role in the assembly of snRNP core particles and may play a role in cytokine-activated transduction pathways. It negatively regulates cyclin E1 promoter activity and cellular proliferation and May regulate the SUPT5H transcriptional elongation properties. It may be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. PRMT5 methylates histone H2A/H4 'Arg-3' during germ cell development and methylates histone H3 'Arg-8', which may repress transcription.
Catalog Number:
(10105-858)
Supplier:
Prosci
Description:
PDLIM5 is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
Catalog Number:
(10099-538)
Supplier:
Prosci
Description:
ZNF503 may function as a transcriptional repressor.
Catalog Number:
(10106-630)
Supplier:
Prosci
Description:
HSFY2 is Y linked hear shock transcription factor.
Catalog Number:
(10103-818)
Supplier:
Prosci
Description:
The function of the C2orf60 protein remains unknown.
Catalog Number:
(10103-950)
Supplier:
Prosci
Description:
The exact function of C16orf71 remains unknown.
Catalog Number:
(10110-938)
Supplier:
Prosci
Description:
AGBL5 belongs to the peptidase M14 family. The exact function of AGBL5 remains unknown.
Supplier:
TCI America
Description:
CAS Number: 53-85-0
MDL Number: MFCD00036785 Molecular Formula: C12H12Cl2N2O4 Molecular Weight: 319.14 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Melting point (°C): 222 Specific rotation [a]20/D: -67 deg (C=2, Pyridine) Lambda max.: 296 nmStorage Temperature: <0°C
Catalog Number:
(TCB4000-25MG)
Supplier:
TCI America
Description:
CAS Number: 65391-42-6
MDL Number: MFCD00058004 Molecular Formula: C16H24N2O4 Molecular Weight: 344.84 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Melting point (°C): 108 Specific rotation [a]20/D: -13 deg (C=0.5, 1mol/L HCl) Storage Temperature: >-20°C
Catalog Number:
(89366-374)
Supplier:
Genetex
Description:
Rabbit Polyclonal Antibody to GATA3
Supplier:
Ace Glass
Description:
This rugged, cylindrical reaction flask has a Duran style flat flange with an o-ring groove
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00149186
Soluble in water. Insoluble in alcohol
Fieser: 1,1107 4,466 15,134
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