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Ace+Method+Development+Kits
Supplier:
MilliporeSigma
Description:
Manganese(II) sulfate monohydrate spray-dried, Grade:ACS,Reag. Ph Eur, CAS number:10034-96-5, Application:for analysis EMSURE
Catalog Number:
(10105-250)
Supplier:
Prosci
Description:
POH1 (pad one homolog-1) is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway
Supplier:
Thermo Scientific Chemicals
Description:
In drying organic liquids, in Kjeldahl nitrogen determination, in manufacturing of glass. Sodium sulfate anhydrous is used primarily for drying non-aqueous solvents by removing traces of water. It is used as a fining agent for molten glass, levelling agent in textile processing, and filler in detergents. It is also used in Kraft process for paper pulping, defrosting windows, manufacture of starch, glass, and soap.
Supplier:
MilliporeSigma
Description:
Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.
Catalog Number:
(10386-762)
Supplier:
Bioss
Description:
P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
Catalog Number:
(10386-766)
Supplier:
Bioss
Description:
P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
Catalog Number:
(10100-696)
Supplier:
Prosci
Description:
The MYCBP gene encodes a protein that binds to the N-terminal region of MYC and stimulates the activation of E box-dependent transcription by MYC.
Supplier:
MilliporeSigma
Description:
Lead(II) hydroxide acetate anhydrous, Grade:ACS, CAS number:51404-69-4, Synonyms:Horne's compound, Application:for the analysis of sugar acc. to Horne EMSURE
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00003494
Beilstein Registry No.: 4154566
Notes: m.p. 851°C (begins to lose CO2 at 400°C). For use as an alkalimetric standard, material should be heated at 285°C for 2 hrs.
Fieser: 7,332
Supplier:
Ace Glass
Description:
Adapters feature a top outer [ST] joint, bottom inner [ST] joint, and side inner [ST] joint
Supplier:
Polyplus Transfection
Description:
LipidBrick® IM21.7c is a novel cationic lipid dedicated to the formulation of lipid nanoparticles (LNPs) for the development of mRNA-based vaccines and therapeutics. LipidBrick® IM21.7c overcomes the challenges posed by the current generation of ionizable lipids used in LNPs, allowing for wider in vivo biodistribution and reduced accumulation in the liver. Proof-of-concept work has demonstrated that the intrinsic properties of LipidBrick® IM21.7c in modulating the overall electrical charge of LNPs extend the in vivo biodistribution and improve both drug efficacy and formulation stability without inducing safety concerns.
Catalog Number:
(10750-720)
Supplier:
Prosci
Description:
FAM59A Antibody: FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
Catalog Number:
(10110-444)
Supplier:
Prosci
Description:
Putative function of SPATA12 is to maintain the cell in a differentiated state and/or to suppress cell proliferation in the human testis.
Catalog Number:
(10110-628)
Supplier:
Prosci
Description:
MICALL1 contains 1 CH (calponin-homology) domain and 1 LIM zinc-binding domain. It may be a cytoskeletal regulator.
Catalog Number:
(10101-968)
Supplier:
Prosci
Description:
AFF2 belongs to the AF4 family. Defects in AFF2 are the cause of FRAXE. The exact function of AFF2 remains unknown.
Catalog Number:
(10110-960)
Supplier:
Prosci
Description:
GSG1 belongs to the GSG1 family. GSG1 may cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.
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