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Catalog Number:
(10491-824)
Supplier:
Bioss
Description:
SHARPIN is a 387 amino acid protein that localizes to the cytoplasm and contains one RanBP2-type zinc finger. Expressed at high levels in placenta and skeletal muscle and present at lower levels in colon, brain, heart, liver, kidney, lung, thymus and small intestine, SHARPIN interacts with Shank 1 and is thought to play a role in the control of inflammatory responses and in the overall development of the immune system. SHARPIN exists as three alternatively spliced isoforms and shares 73% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding SHARPIN maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Catalog Number:
(10487-848)
Supplier:
Bioss
Description:
NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Catalog Number:
(10110-808)
Supplier:
Prosci
Description:
RPESP belongs to the thrombospondin family. It contains 1 SMB (somatomedin-B) domain and 1 TSP type-1 domain. The exact function of RPESP remains unknown.
Catalog Number:
(10102-782)
Supplier:
Prosci
Description:
RNF207 contains 1 B box-type zinc finger and 1 RING-type zinc finger. The function of the RNF207 protein remains unknown.
Catalog Number:
(10101-770)
Supplier:
Prosci
Description:
CCT8L2 belongs to the TCP-1 chaperonin family. It possible molecular chaperone and assists the folding of proteins upon ATP hydrolysis.
Catalog Number:
(10106-794)
Supplier:
Prosci
Description:
Mouse Ces6 is a member of carboxylesterases family. Carboxylesterases are enzymes that catalyze the hydrolysis of a wide range of ester-containing endogenous and xenobiotic compounds.
Catalog Number:
(10496-118)
Supplier:
Bioss
Description:
ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.
Catalog Number:
(10496-408)
Supplier:
Bioss
Description:
ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.
Catalog Number:
(10104-330)
Supplier:
Prosci
Description:
IFNA7 belongs to the alpha/beta interferon family. IFNA7 is produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Catalog Number:
(10107-070)
Supplier:
Prosci
Description:
ZNF31contains 1 KRAB domain and 10 C2H2-type zinc fingers. ZNF31 belongs to the krueppel C2H2-type zinc-finger protein family and may be involved in transcriptional regulation.
Catalog Number:
(10103-984)
Supplier:
Prosci
Description:
RP13-102H20.1 is the GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Catalog Number:
(10105-220)
Supplier:
Prosci
Description:
PSMD6 acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Supplier:
Ace Glass
Description:
Octagonal-shaped, PTFE stirrer magnets feature a large 25mm (1") pivot ring (PTFE collar).
Catalog Number:
(10099-660)
Supplier:
Prosci
Description:
ZNF471 belongs to the krueppel C2H2-type zinc-finger protein family. Itcontains 15 C2H2-type zinc fingers and 1 KRAB domain. ZNF471 may be involved in transcriptional regulation.
Catalog Number:
(10103-798)
Supplier:
Prosci
Description:
ZFYVE19 contains 1 FYVE-type zinc finger. A chromosomal aberration, translocation t (11;15) (q23;q14) with MLL/HRX, involving ZFYVE19 is associated with acute myeloblastic leukemia (AML).
Catalog Number:
(10099-792)
Supplier:
Prosci
Description:
SLC15A2 belongs to the PTR2/POT transporter (TC 2.A.17) family. It is a multi-pass membrane protein. The expression/activity of PEPT2 (SLC15A2) may be a critical factor in the modulation of opioidergic neurotransmission in vivo.
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