Ace+Method+Development+Kits
Catalog Number:
(TCD4537-200MG)
Supplier:
TCI America
Description:
CAS Number: 149809-43-8
MDL Number: MFCD13195567 Molecular Formula: C21H21F2N3O4S Molecular Weight: 449.47 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 107 Specific rotation [a]20/D: -42 deg (C=1, CHCl3) Storage Temperature: >-20°C
Supplier:
AGILENT TECHNOLOGIES, INC (CSD) CA
Description:
A simple and cost-effective way to increase sample throughput with existing GC or GC/MS instruments.
Supplier:
Hach
Description:
The TL23 series benchtop turbidimeters for a wide range of turbidity applications feature the trusted technology of Hach’s legacy benchtop turbidimeters and improved functionality to simplify testing.
![]()
Catalog Number:
(SXS-3165)
Supplier:
SPEX CERTIPREP LLC
Description:
Analytical Standards for Medicinal and Recreational Cannabis Testing
Residual Solvent Single Standard While the legalization of cannabis for both medicinal and recreational purposes has been gaining speed, legislation and regulation has not necessarily kept pace. Out of a drive for self-regulation and significant consumer safety concerns, many producers and manufacturers are turning to testing labs in order to ensure that their products are of high quality and free of chemical contaminants. SPEX CertiPrep offers ISO/IEC 17025 and ISO 17034 Certified Reference Materials (CRMs) for all of the common contaminants such as pesticide residues, residual solvents and heavy metals, as well as qualitative analysis CRMs, such as terpenes. As the industry demands change and regulations are put into place, we continually update our product offering. Designed for Methods: State specific pesticide regulations: • OAR 333-008-11 • HB 3460 • AOAC 2007-01 • EN 15662
Catalog Number:
(SXS-2555)
Supplier:
SPEX CERTIPREP LLC
Description:
Analytical Standards for Medicinal and Recreational Cannabis Testing
Residual Solvent Single Standard While the legalization of cannabis for both medicinal and recreational purposes has been gaining speed, legislation and regulation has not necessarily kept pace. Out of a drive for self-regulation and significant consumer safety concerns, many producers and manufacturers are turning to testing labs in order to ensure that their products are of high quality and free of chemical contaminants. SPEX CertiPrep offers ISO/IEC 17025 and ISO 17034 Certified Reference Materials (CRMs) for all of the common contaminants such as pesticide residues, residual solvents and heavy metals, as well as qualitative analysis CRMs, such as terpenes. As the industry demands change and regulations are put into place, we continually update our product offering. Designed for Methods: State specific pesticide regulations: • OAR 333-008-11 • HB 3460 • AOAC 2007-01 • EN 15662
Catalog Number:
(ABCA_AB241461-100U)
Supplier:
ABCAM INC.
Description:
Anti-Histone H3 (acetyl K56) Rabbit Polyclonal Antibody
Catalog Number:
(89359-746)
Supplier:
Genetex
Description:
CD40 (48 to 50 kDa) is a transmembrane glycoprotein mainly expressed on the surface of B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions, central to the control of thymus dependent humoral immunity and may be critical in the development of cell mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
Catalog Number:
(CA709-1931)
Catalog Number:
(CA709-1331)
Catalog Number:
(76108-674)
Supplier:
Bioss
Description:
Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
Catalog Number:
(CA102-4101)
Supplier:
Rockland Immunochemical
Description:
Primary Rabbit Anti-CAT SERUM Reacts with Cat (Feline)
Catalog Number:
(10372-582)
Supplier:
Bioss
Description:
Smad2 is a 58 kDa member of a family of proteins involved in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor-regulated Smad's, activin/TGF alpha receptor-regulated (Smad2 and 3) or BMP receptor regulated (Smad1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smad's; and the inhibitory Smad's, (Smad6 and Smad7). Smad2 consists of two highly conserved domains, the N terminal Mad homology (MH1) and the C-terminal Mad homology 2 (MH2) domains. The MH1 domain binds DNA and regulates nuclear import and transcription while the MH2 domain conserved among all the Smad's regulates Smad2 oligomerization and binding to cytoplasmic adaptors and transcription factors. Activated Smad2 associates with Smad4 and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. This translocation of Smad2 (as well as Smad3) into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin binding region of the MH1 domain by extracellular signal regulated kinase 1(ERK 1) enhances Smad2 transcriptional activity, which is negatively regulated by calmodulin. The regulation of Smad2 phosphorylation on threonine 8 by ERK 1 and calmodulin is critical for Smad2 mediated signaling.
Catalog Number:
(10372-576)
Supplier:
Bioss
Description:
Smad2 is a 58 kDa member of a family of proteins involved in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor-regulated Smad's, activin/TGF alpha receptor-regulated (Smad2 and 3) or BMP receptor regulated (Smad1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smad's; and the inhibitory Smad's, (Smad6 and Smad7). Smad2 consists of two highly conserved domains, the N terminal Mad homology (MH1) and the C-terminal Mad homology 2 (MH2) domains. The MH1 domain binds DNA and regulates nuclear import and transcription while the MH2 domain conserved among all the Smad's regulates Smad2 oligomerization and binding to cytoplasmic adaptors and transcription factors. Activated Smad2 associates with Smad4 and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. This translocation of Smad2 (as well as Smad3) into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin binding region of the MH1 domain by extracellular signal regulated kinase 1(ERK 1) enhances Smad2 transcriptional activity, which is negatively regulated by calmodulin. The regulation of Smad2 phosphorylation on threonine 8 by ERK 1 and calmodulin is critical for Smad2 mediated signaling.
Supplier:
Burdick & Jackson
Description:
For HPLC, liquid and gas chromatography, pesticide residue analysis, spectophotometry, organic synthesis and combinatorial chemistry.
Catalog Number:
(10483-016)
Supplier:
Bioss
Description:
Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.
To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is currently unavailable but limited stock may be available in our extended warehouse network. Please call 1-800-932-5000 and a VWR Customer Service Representative will help you.
|
|||||||||