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Ace+Method+Development+Kits
Catalog Number:
(10495-720)
Supplier:
Bioss
Description:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00149813
Notes: m.p. 100°C -5H2O, 280°C -6H2O
Supplier:
TCI America
Description:
CAS Number: 134127-48-3
MDL Number: MFCD03093252 Molecular Formula: C47H47ClN2O3S Molecular Weight: 755.41 Purity/Analysis Method: >98.0% (HPLC,N) Form: Crystal Lambda max.: 813 nm (MeOH)
Catalog Number:
(CA95046-108)
Supplier:
Enzo Life Sciences
Description:
Hsp 110 belongs to a family of large stress proteins known as the Hsp110/SSE family, the mostly overlooked relatives of the well studied Hsp70 family. Members of this group, while significantly larger and containing sequences not present in the Hsp70 family, share 30-33% amino acid identity with members of the Hsp70 family, mostly in the conserved ATP-binding domain. Presently, all identified members of the Hsp70-like sequences belong to either the Hsp70 family or the Hsp110/SSE family. Hsp110 appears to be a normal constituent of mammalian cells with highest expression in the brain, and its induction by heat shock strongly correlates with cellular thermotolerance. Hsp110 may contribute to RNA stability, and its capacity to bind peptide has made Hsp110 a promising immunoadjuvant in anti-tumor vaccine development.
Supplier:
Anaspec Inc
Description:
This human Angiotensin I (Ang I) sequence also corresponds to horse, sheep, pig, and rat Ang I. Ang I is cleaved to Ang II by the angiotensin-converting enzyme (ACE). There is also evidence for non-angiotensin-converting enzyme-dependent conversion of Ang I to Ang II. Human chymase efficiently converts the 10-mer Ang I to the 8-mer hormone Ang II by splitting the Phe8-His9 bond in Ang I.
Sequence: DRVYIHPFHL MW: 1296.5 Da % Peak area by HPLC: 95 Storage condition: -20°C
Catalog Number:
(ABCA_AB251549-100U)
Supplier:
ABCAM INC.
Description:
Anti-Histone H3 (acetyl K64) Rabbit Monoclonal Antibody [clone: EPR20713]
Catalog Number:
(ABCA_AB241151-100U)
Supplier:
ABCAM INC.
Description:
Anti-Histone H3 (acetyl K9) Rabbit Monoclonal Antibody [clone: EPR21239]
Catalog Number:
(10107-046)
Supplier:
Prosci
Description:
SATB1 binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. SATB1 was thought to recognize the sugar-phosphate structure of double-stranded DNA
Catalog Number:
(10104-672)
Supplier:
Prosci
Description:
EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25.
Catalog Number:
(10109-506)
Supplier:
Prosci
Description:
This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.
Catalog Number:
(10111-244)
Supplier:
Prosci
Description:
NANOG is a new marker for testicular carcinoma in situ and germ cell tumors. Gene knockdown of Nanog promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal.
Catalog Number:
(CA76333-724)
Supplier:
GE Healthcare - Life Sciences
Description:
HiScreen columns prepacked with Capto Core 400 designed for intermediate purification and polishing of viruses and other large biomolecules.
Catalog Number:
(10092-394)
Supplier:
Proteintech
Description:
PKM2, also named as OIP3, PK2, PK3, PKM, p58, THBP1, CTHBP and Tumor M2-PK, belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. It stimulates POU5F1-mediated transcriptional activation. PKM2 plays a general role in caspase independent cell death of tumor cells. PKM2, Pyruvate kinase isozymes M1/M2, has 2 isoforms .The immunogen of this antibody is M1 isoform, also called PKM1. By the upstream metabolite fructose-1,6-bisphosphate, PKM1 is a constitutively active enzyme.The primary pyruvate kinase isoform before tumour development is PK-M1; however, the primary isoform from four independent tumours is PK-M2. This antibody is specific to PKM1 isoform.
Catalog Number:
(10089-170)
Supplier:
Proteintech
Description:
GLS, also named as GLS1 and KIAA0838, belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. Ping Gao et al. (2009) determined that mitochondrial glutaminase expression (GLS, molecular mass of ~58 kDa) is increased ~10-fold in response to Myc. It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. GLS has 3 isoforms produced by alternative splicing and this antibody is specific to the 3 isoforms(KGA,GAM,GAC) of GLS.
Catalog Number:
(CAAAA16077-06)
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