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Ace+Method+Development+Kits
Catalog Number:
(10355-838)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.
Catalog Number:
(10750-726)
Supplier:
Prosci
Description:
SIPA1L3 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
Catalog Number:
(76120-324)
Supplier:
Bioss
Description:
Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family.
Supplier:
TCI America
Description:
Tris(phenylthio)methane, Purity/Analysis Method: >98.0%(GC), CAS Number: 4832-52-4, Molecular formula: C19H16S3, Molecular weight: 340.52, Size: 25G
Supplier:
TCI America
Description:
N,N,N',N'-Tetrakis(4-nitrophenyl)-1,4-phenylenediamine, Purity/Analysis Method: >98.0%(N), CAS Number: 3283-05-4, Molecular Formula: C30H20N6O8, Molecular Weight: 592.52, Size: 5G
Supplier:
TCI America
Description:
CAS Number: 24194-61-4
MDL Number: MFCD00010048 Molecular Formula: C10H20S4 Molecular Weight: 268.51 Purity/Analysis Method: >98.0% (GC) Form: Crystal Color: White Melting point (°C): 123
Catalog Number:
(TCN0599-100MG)
Supplier:
TCI America
Description:
CAS Number: 196-42-9
MDL Number: MFCD00191469 Molecular Formula: C24H14 Molecular Weight: 302.38 Purity/Analysis Method: >98.0% (GC) Form: Crystal
Supplier:
TCI America
Description:
CAS Number: 1287-16-7
MDL Number: MFCD00045464 Molecular Formula: C12H12FeO2 Molecular Weight: 244.07 Purity/Analysis Method: >97.0% (GC) Form: Crystal
Supplier:
TCI America
Description:
CAS Number: 4370-02-9
Molecular Formula: C9H10O2 Molecular Weight: 150.18 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 158
Catalog Number:
(TCB0319-100MG)
Supplier:
TCI America
Description:
CAS Number: 66138-05-4
MDL Number: MFCD00060026 Molecular Formula: C15H15ClN4 Molecular Weight: 286.76 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 243
Catalog Number:
(TCB1740-001G)
Supplier:
TCI America
Description:
CAS Number: 101460-22-4
MDL Number: MFCD00191620 Molecular Formula: C10H11BrO5 Molecular Weight: 291.10 Purity/Analysis Method: >97.0% (T) Form: Crystal Melting point (°C): 96
Supplier:
TCI America
Description:
CAS Number: 51-36-5
MDL Number: MFCD00002494 Molecular Formula: C7H4Cl2O2 Molecular Weight: 191.01 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 187
Supplier:
TCI America
Description:
CAS Number: 148720-07-4
MDL Number: MFCD00191442 Molecular Formula: C8H9N3O2 Molecular Weight: 275.28 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 228
Supplier:
TCI America
Description:
CAS Number: 68922-18-9
MDL Number: MFCD00006365 Molecular Formula: C7H9NO3S Molecular Weight: 187.21 Purity/Analysis Method: >95.0% (T) Form: Crystal Melting point (°C): 268
Catalog Number:
(TCH1036-5G)
Supplier:
TCI America
Description:
CAS Number: 105969-98-0
MDL Number: MFCD01115771 Molecular Formula: C8H4N2O5 Molecular Weight: 208.13 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 169
Supplier:
TCI America
Description:
CAS Number: 497-37-0
Molecular Formula: C7H12O Molecular Weight: 112.17 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 177 Melting point (°C): 128
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