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Ace+Method+Development+Kits
Catalog Number:
(10353-352)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation.
Catalog Number:
(10393-992)
Supplier:
Bioss
Description:
Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.
Supplier:
TCI America
Description:
CAS Number: 720-44-5
MDL Number: MFCD00014398 Molecular Formula: C14H14O2 Molecular Weight: 214.26 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 65
Catalog Number:
(TCC2297-1G)
Supplier:
TCI America
Description:
CAS Number: 92-45-5
MDL Number: MFCD00024073 Molecular Formula: C9H5ClO2 Molecular Weight: 180.59 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 123
Supplier:
TCI America
Description:
CAS Number: 18278-34-7
MDL Number: MFCD00051964 Molecular Formula: C8H8O3 Molecular Weight: 152.15 Purity/Analysis Method: >97.0% (GC,T) Form: Crystal Melting point (°C): 158
Supplier:
TCI America
Description:
CAS Number: 107-58-4
MDL Number: MFCD00026271 Molecular Formula: C7H13NO Molecular Weight: 127.19 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 130
Supplier:
TCI America
Description:
CAS Number: 140-89-6
MDL Number: MFCD00004931 Molecular Formula: C3H6OS2 Molecular Weight: 160.29 Purity/Analysis Method: >95.0% (T) Form: Crystal Melting point (°C): 210 Flash Point (°C): 96
Supplier:
TCI America
Description:
CAS Number: 3011-89-0
MDL Number: MFCD00017119 Molecular Formula: C7H5ClN2O3 Molecular Weight: 200.58 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 171
Catalog Number:
(TCB4008-5G)
Supplier:
TCI America
Description:
CAS Number: 78600-31-4
Molecular Formula: C18H14BrN Molecular Weight: 324.22 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 165 Melting point (°C): 63
Catalog Number:
(TCF0735-5G)
Supplier:
TCI America
Description:
CAS Number: 84163-77-9
MDL Number: MFCD03236724 Molecular Formula: C12H13FN2O Molecular Weight: 220.25 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 306
Supplier:
TCI America
Description:
CAS Number: 33626-98-1
MDL Number: MFCD00100408 Molecular Formula: C12H9BrO2 Molecular Weight: 265.11 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 125
Catalog Number:
(TCN0925-5G)
Supplier:
TCI America
Description:
CAS Number: 152873-79-5
Molecular Formula: C12H6F6O6S2 Molecular Weight: 424.28 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 115
Catalog Number:
(TCM1641-1G)
Supplier:
TCI America
Description:
CAS Number: 303127-80-2
Molecular Formula: C20H24O7 Molecular Weight: 376.41 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Storage Temperature: <0°C
Catalog Number:
(TCF0425-025G)
Supplier:
TCI America
Description:
CAS Number: 399-10-0
MDL Number: MFCD00017961 Molecular Formula: C15H11FO Molecular Weight: 226.25 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 80
Supplier:
TCI America
Description:
CAS Number: 126716-90-3
MDL Number: MFCD00142505 Molecular Formula: C18H14O4 Molecular Weight: 294.31 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 136
Supplier:
TCI America
Description:
CAS Number: 4464-18-0
MDL Number: MFCD01108484 Molecular Formula: C9H12O3 Molecular Weight: 168.19 Purity/Analysis Method: >95.0% (GC) Form: Crystal Melting point (°C): 78
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