Ace+Method+Development+Kits
Catalog Number:
(10353-372)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation.
Supplier:
TCI America
Description:
CAS Number: 93-62-9
MDL Number: MFCD00004293 Molecular Formula: C6H11NO5 Molecular Weight: 177.16 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 177
Catalog Number:
(10353-342)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
Catalog Number:
(10353-346)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
Catalog Number:
(TCD1611-005G)
Supplier:
TCI America
Description:
CAS Number: 609-86-9
MDL Number: MFCD00007682 Molecular Formula: C7H5I2NO2 Molecular Weight: 388.93 Purity/Analysis Method: >97.0% (T) Form: Crystal Melting point (°C): 243
Supplier:
TCI America
Description:
CAS Number: 2328-12-3
MDL Number: MFCD00012744 Molecular Formula: C11H15NO2 Molecular Weight: 229.70 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 248
Catalog Number:
(TCD0212-025G)
Supplier:
TCI America
Description:
CAS Number: 39150-45-3
MDL Number: MFCD00014783 Molecular Formula: C6H6Br2N2O2S Molecular Weight: 329.99 Purity/Analysis Method: >97.0% (T) Form: Crystal Melting point (°C): 242
Supplier:
TCI America
Description:
CAS Number: 2901-80-6
MDL Number: MFCD00038283 Molecular Formula: C12H15NO3 Molecular Weight: 221.26 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 132
Supplier:
TCI America
Description:
CAS Number: 1755-15-3
Molecular Formula: C10H14O3 Molecular Weight: 182.22 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 36
Supplier:
TCI America
Description:
CAS Number: 789-25-3
MDL Number: MFCD00003003 Molecular Formula: C18H16Si Molecular Weight: 260.41 Purity/Analysis Method: >96.0% (GC) Form: Crystal Color: White Boiling point (°C): 184 Melting point (°C): 46 Flash Point (°C): 76
Supplier:
TCI America
Description:
CAS Number: 4551-69-3
MDL Number: MFCD00003136 Molecular Formula: C17H14N2O2 Molecular Weight: 278.31 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 118
Supplier:
TCI America
Description:
CAS Number: 306934-80-5
MDL Number: MFCD09064936 Molecular Formula: C5H4N2O3 Molecular Weight: 140.10 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 257
Supplier:
TCI America
Description:
CAS Number: 18698-96-9
MDL Number: MFCD00046546 Molecular Formula: C8H7IO2 Molecular Weight: 262.05 Purity/Analysis Method: >97.0% (GC,T) Form: Crystal Melting point (°C): 117
Catalog Number:
(TCT1671-025G)
Supplier:
TCI America
Description:
CAS Number: 622-00-4
MDL Number: MFCD00674554 Molecular Formula: C18H18O6 Molecular Weight: 330.34 Purity/Analysis Method: >97.0% (GC) Form: Crystal Color: White Melting point (°C): 68 Specific rotation [a]20/D: -13 deg (C=1, Acetone)
Supplier:
TCI America
Description:
CAS Number: 31366-25-3
MDL Number: MFCD00005492 Molecular Formula: C6H4S4 Molecular Weight: 204.34 Purity/Analysis Method: >98.0% (GC) Form: Crystal Color: Reddish Yellow Melting point (°C): 120 Lambda max.: 369 nm (CHCl3)
Supplier:
TCI America
Description:
CAS Number: 728-87-0
MDL Number: MFCD00008410 Molecular Formula: C15H16O3 Molecular Weight: 244.29 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 70
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