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Ace+Method+Development+Kits
Catalog Number:
(10353-348)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
Catalog Number:
(10353-340)
Supplier:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
Catalog Number:
(TCD2367-5G)
Supplier:
TCI America
Description:
CAS Number: 2449-35-6
MDL Number: MFCD00020375 Molecular Formula: C14H10O6S Molecular Weight: 306.29 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 370
Supplier:
TCI America
Description:
CAS Number: 52709-86-1
MDL Number: MFCD00183206 Molecular Formula: C16H15NO Molecular Weight: 237.30 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 73 Lambda max.: 294 nm (EtOH)
Catalog Number:
(76119-868)
Supplier:
Bioss
Description:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Catalog Number:
(TCT1124-100G)
Supplier:
TCI America
Description:
CAS Number: 3115-68-2
MDL Number: MFCD00011853 Molecular Formula: C16H36BrP Molecular Weight: 339.34 Purity/Analysis Method: >99.0% (T) Form: Crystal Color: White Melting point (°C): 104 Flash Point (°C): 290
Supplier:
TCI America
Description:
CAS Number: 111109-77-4
MDL Number: MFCD00210047 Molecular Formula: C8H18O3 Molecular Weight: 162.23 Purity/Analysis Method: >94.0% (GC) Form: Clear Liquid Flash Point (°C): 65 Specific Gravity (20/20): 0.90
Supplier:
TCI America
Description:
CAS Number: 34590-94-8
MDL Number: MFCD00059604 Molecular Formula: C7H16O3 Molecular Weight: 148.20 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 188 Melting point (°C): -80 Flash Point (°C): 77 Specific Gravity (20/20): 0.95
Catalog Number:
(TCI0874-5G)
Supplier:
TCI America
Description:
CAS Number: 62067-45-2
MDL Number: MFCD01734696 Molecular Formula: C10H18O2 Molecular Weight: 170.25 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 134 Specific Gravity (20/20): 0.99
Supplier:
TCI America
Description:
CAS Number: 18368-76-8
Molecular Formula: C6H6ClN Molecular Weight: 127.57 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 193 Flash Point (°C): 79 Specific Gravity (20/20): 1.17
Supplier:
TCI America
Description:
CAS Number: 174500-20-0
MDL Number: MFCD01863586 Molecular Formula: C23H19N3O2 Molecular Weight: 369.42 Purity/Analysis Method: >95.0% (HPLC) Form: Crystal Melting point (°C): 164 Specific rotation [a]20/D: -175 deg (C=1, CH2Cl2)
Supplier:
TCI America
Description:
CAS Number: 132388-68-2
MDL Number: MFCD00153299 Molecular Formula: C28H30N2O5 Molecular Weight: 474.56 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 202 Specific rotation [a]20/D: -21 deg (C=1, MeOH)
Supplier:
Hach
Description:
For determination of volatile acids by the esterification method.
Supplier:
TCI America
Description:
CAS Number: 2103-91-5
MDL Number: MFCD00170264 Molecular Formula: C10H10N2S Molecular Weight: 190.26 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 137 Lambda max.: 266 nm (EtOH)
Catalog Number:
(TCD3898-1G)
Supplier:
TCI America
Description:
CAS Number: 117384-45-9
MDL Number: MFCD00192000 Molecular Formula: C12H22O6 Molecular Weight: 262.30 Purity/Analysis Method: >97.0% (GC) Form: Crystal Melting point (°C): 90 Specific rotation [a]20/D: 11 deg (C=1, Acetone)
Supplier:
TCI America
Description:
CAS Number: 65355-00-2
MDL Number: MFCD02093485 Molecular Formula: C20H22O2 Molecular Weight: 294.39 Purity/Analysis Method: >99.0% (GC) Form: Crystal Melting point (°C): 167 Specific rotation [a]20/D: -50 deg (C=1, CHCl3)
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