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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Catalog Number:
(76079-466)
Supplier:
Bioss
Description:
Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
Supplier:
PIP
Description:
Multipurpose 100% cotton gloves offer comfortable light protection.
Catalog Number:
(10090-632)
Supplier:
Proteintech
Description:
NDUFA4L2(NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2), also named as NUOMS, is a HIF-1α target gene that localizes to the mitochondria and belongs to the complex I NDUFA4 subunit family. It downregulates oxygen consumption and Complex I activity in hypoxia. NDUFA4L2 is involved in hypoxic adaptation by decreasing mitochondrial ROS production.
Catalog Number:
(76079-718)
Supplier:
Bioss
Description:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Catalog Number:
(10355-580)
Supplier:
Bioss
Description:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
Catalog Number:
(76520-578)
Supplier:
KEYSTONE ADJUSTABLE CAP CO., INC.
Description:
1422A Tyvek® protective covers help faciliate aseptic assembly and installation of pharmaceutical change parts.
Catalog Number:
(77440-212)
Supplier:
Bioss
Description:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
Catalog Number:
(10459-738)
Supplier:
Bioss
Description:
Produced by macrophages, IFN alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Catalog Number:
(76116-376)
Supplier:
Bioss
Description:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Catalog Number:
(10459-742)
Supplier:
Bioss
Description:
Produced by macrophages, IFN alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Catalog Number:
(10342-810)
Supplier:
Bioss
Description:
Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Catalog Number:
(10459-732)
Supplier:
Bioss
Description:
Produced by macrophages, IFN alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Catalog Number:
(RK32002)
Supplier:
Restek
Description:
Standards are packaged in hexane at the stated concentrations in 1 mL ampoules.
Catalog Number:
(19760-060)
Supplier:
Medegen Medical Products, LLC
Description:
This instrument tray has a satin finish, smooth rounded corners, and open beads for easy cleaning
Supplier:
Thermo Fisher Scientific
Description:
Cell factory units maximize available growing area with low risk of contamination and easy handling
Catalog Number:
(10340-356)
Supplier:
Bioss
Description:
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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