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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Supplier:
Remco Products
Description:
This extendable handle is often used with the pad holder and deck scrubs for reaching high walls and tanks.
Catalog Number:
(10032-018)
Supplier:
YSI
Description:
The ORP15A is part of the EcoSense® family of products. The ORP15A offers accurate, low-cost measurement of ORP (absolute and relative) along with temperature.
Supplier:
Enzo Life Sciences
Description:
Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.
Supplier:
Bachem Americas
Description:
For other opioid peptides see, the product families ‘Deltorphins and Dermorphins’, ‘Endorphins, MPF, Neoendorphins’, and ‘Opioid Peptides'.
Supplier:
Thermo Fisher Scientific
Description:
Flexible, durable, high-purity tubing is designed for a variety of pump and transfer applications, including those in the pharmaceutical, research laboratory, bioprocess manufacturing, food and beverage, and semiconductor industries.
Supplier:
Sheldon Manufacturing
Description:
Gravity convection laboratory ovens are recommended for critical scientific and analytical use in laboratory and pilot plant product research. Typical applications include aging, curing, drying, baking, pre-heating, conditioning and life cycle testing.
Supplier:
Genscript
Description:
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.351 (a.k.a. 20H/501Y.V2) is a variant of SARS-CoV-2. It has multiple mutations in the RBD, including K417N, E484K, N501Y. Lineage B.1.1.7 (a.k.a. 20I/501Y.V1) is also a variant of SARS-CoV-2 and has a mutation called N501Y in the RBD.SARS-CoV-2 Spike (E484) Neutralizing Antibody (COV2109) is produced from cell culture <i>in vitro</i> under conditions free from animal-derived components. The product is a humanized neutralizing antibody, recognizing E484 site of wild-type RBD. When E484 is mutated to E484K, the mutant RBD, such as RBD (B.1.351) as seen in Figure 1, can’t be recognized by the product.
Catalog Number:
(10492-494)
Supplier:
Bioss
Description:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM78B gene product has been provisionally designated FAM78B pending further characterization.
Catalog Number:
(10479-786)
Supplier:
Bioss
Description:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM102B gene product has been provisionally designated FAM102B pending further characterization.
Catalog Number:
(10102-550)
Supplier:
Prosci
Description:
CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, CA8 lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). CA8 continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
Supplier:
Colder Products
Description:
These quick disconnect couplings cover a wide range of general purpose applications from chemical analyzers to medical devices
Supplier:
MilliporeSigma
Description:
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.
Supplier:
Bel-Art Products
Description:
For Sterilizing Tray, model 62662-423. Fits outside tray rim (25.4mm skirt); 3.2mm thick. Steam autoclavable at 121[degree]C.
Supplier:
PIP
Description:
Cleanteam® Light weight seamless knit clean environment glove with rolled hem cuff ideal for inspection and electronics assembly.
Supplier:
Caron Products
Description:
Caron's new 7350-Series Animal Rearing Chambers provide the results users need, without all the usual hassle.
Supplier:
Thermo Scientific Chemicals
Description:
A natural product from green tea that induces apoptosis
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