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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Catalog Number:
(CA103307-278)
Supplier:
New England Biolabs (NEB)
Description:
Nuclease-free Water is ideal for the preparation of reagents and for use in enzymatic reactions. No toxic agents, such as DEPC, are used in the production of this water, so as to avoid inhibition in enzymatic reactions.
Catalog Number:
(700010-154)
Supplier:
Spectrum Chemicals
Description:
Tropaeolin O, also known as Chrysoine resorcinol or Yellow T, is a synthetic azo dye used as a pH indicator.
Supplier:
Thermo Scientific
Description:
Save time and minimize the risk of cross-contamination with Thermo Scientific™ SureSTART™ Level 3 WebSeal™ 96-well plate sealing mats for well plate kits. Select SureSTART Level 3 products for ultimate performance and sensitivity from your methods while maintaining the highest levels of sample security and integrity.
Catalog Number:
(89359-898)
Supplier:
Genetex
Description:
Retinoblastoma gene product (RB) is a tumor suppressor protein and acts as cell cycle regulator. Recently, RB has been shown to play a role in apoptosis. During apoptosis, RB is subjected to cleavage by caspase 3 like protease. Caspase 3 cleaves RB into 48 and 68kDa fragments. Cleavage of RB would make it functionally inactive, causing release of E2F 1. The E2F 1 then may promote apoptosis.
Catalog Number:
(76338-136)
Supplier:
Marlin Steel Wire Products
Description:
Rugged material handling basketand dividers to constain small parts in pockets.
Catalog Number:
(10427-404)
Supplier:
Bioss
Description:
Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells. The expression of MLL-AF-4 influences the production of protein cyclin-dependent kinase inhibitor (CDKN1B), suggesting that inhibition of MLL-AF-4 expression may be a powerful and highly specific treatment of chemotherapy-resistant leukemia.
Catalog Number:
(70690-196)
Supplier:
Bel-Art Products
Description:
Convenient polypropylene holder clips onto the edge of a beaker or other vessel and holds a thermometer vertically near the side of the container for safe and easy reading.
Catalog Number:
(76457-552)
Supplier:
ELPRO SERVICES, INC.
Description:
The LIBERO CS is the PDF logger that simplifies the shipment process for products with known stability data.
Catalog Number:
(76120-158)
Supplier:
Bioss
Description:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The LOC387856 gene product has been provisionally designated LOC387856 pending further characterization.
Catalog Number:
(76120-560)
Supplier:
Bioss
Description:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf42 gene product has been provisionally designated C12orf42 pending further characterization.
Catalog Number:
(76108-374)
Supplier:
Bioss
Description:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM101A gene product has been provisionally designated FAM101A pending further characterization.
Catalog Number:
(89358-214)
Supplier:
Genetex
Description:
Juvenile nephronophthsis, an autosomal recessive cystic kidney disease, is the primary cause for chronic renal failure in children. The gene for nephronophthsis type 1 (NPHP1) has recently been identified. Its gene product, nephrocystin, is a novel protein of unknown function, which contains a src-homology 3 domain.NPHP1 expression has been studied in mouse and human systems. Expression in the human adult is widespread but relatively weak. In contrast, expression in adult mouse is strong and localized to the testis. In situ hybridization to whole mouse embryo demonstrates widespread and consistently strong expression throughout all developmental stages.It is hypothesized that the NPHP1 gene product, nephrocystin, is involved in signaling processes at focal adhesions (cell and extracellular matrix contact) and/or adherens junctions (cell-cell contact). The hypothesis is based on the fact that most src-homology 3 -containing proteins are part of focal adhesion signaling complexes. Additionally, nephrocystin binds to p130(cas), a prominent participant in focal adhesion signaling.
Catalog Number:
(CA89006-808)
Supplier:
3M
Description:
3M™ E-A-Rsoft™ metal detectable earplugs were specially developed for food processing and other industries where it is critical to keep earplugs from contaminating products and processes.
Catalog Number:
(RK30056)
Supplier:
Restek
Description:
Standards are packaged in purge-and-trap-grade methanol at a concentration of 2000 µg/mL in a 1 mL ampoule.
Catalog Number:
(76198-392)
Supplier:
Genscript
Description:
The product is specific for Nivolumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01848-40, Anti- Nivolumab Antibody (6G5H2E6), mAb, Mouse.
Catalog Number:
(10671-700)
Supplier:
Bioss
Description:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
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