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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Catalog Number:
(10107-428)
Supplier:
Prosci
Description:
Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of ILF3.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
Supplier:
Remco Products
Description:
This two-in-one tool is handy for both mixing and scraping, and is great for a variety of applications such as soup, confectionery, dough, and sauce manufacturing as well as many other food processing or other mixing tasks
Catalog Number:
(89155-196)
Supplier:
Enzo Life Sciences
Description:
High mobility group 1 protein (HMGB1) is a chromatin component that is either passively released from necrotic cells or actively secreted in response to angiogenic and inflammatory signals. HMGB1 itself may signal through the receptor for advanced glycation end products (RAGE), and via the Toll-like receptors, TLR2 and TLR4. HMGB1 functions as a late mediator of immune response. Apoptotic cells also release HMGB1 but in an oxidized form that does not trigger the immune response.
Catalog Number:
(10389-266)
Supplier:
Bioss
Description:
This gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq].
Supplier:
Puritan Medical Products
Description:
This specialty foam tipped applicator is produced with chemical resistant foam.
Catalog Number:
(47750-258)
Supplier:
Bel-Art Products
Description:
These durable cabinets are made from 6.35 mm thick acrylic.
Catalog Number:
(76083-850)
Supplier:
Bioss
Description:
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Catalog Number:
(76080-650)
Supplier:
Bioss
Description:
Neurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.
Catalog Number:
(75789-794)
Supplier:
Prosci
Description:
Interferon alpha-6 (IFN- alpha6) is a secreted protein which belongs to the alpha/ beta interferon family. IFN- alpha6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN- alpha6 contains interferon alpha, beta and delta domain. IFN- alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Supplier:
New England Biolabs (NEB)
Description:
NEBNext Multiplex Oligos provide adaptors and primers to enable high yield multiplex Illumina library production. Unique Dual Index (UDI) primer pairs enable the identification and mitigation of the impacts of index hopping when using a patterened flow cell.
Catalog Number:
(10399-198)
Supplier:
Bioss
Description:
High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
Catalog Number:
(RK31451)
Supplier:
Restek
Description:
EPA method 8330 is used to measure explosives residues in water and soil samples, using HPLC with UV detection. Target analytes are nitroaromatic and nitramine explosives and their degradation products. Obtaining pure, neat compounds for Method 8330 reference standards can be very difficult. To ensure the highest quality standards, Restek's Quality Control (QC) lab confirms the identity and purity of mixture components and solvents using one or more of the following techniques: GC-FID, HPLC, GC-ECD, GC-MS, LC-MS, refractive index, and melting point.
Catalog Number:
(74950-138)
Supplier:
Bel-Art Products
Description:
This all-polypropylene rack provides efficient and extended cooling of twenty-eight 50 mL centrifuge tubes in a chilled bath.
Catalog Number:
(10392-614)
Supplier:
Bioss
Description:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
Catalog Number:
(10814-198)
Supplier:
Prosci
Description:
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Catalog Number:
(10085-454)
Supplier:
Proteintech
Description:
CYB5R3, also named as DIA1 and B5R, belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. It plays an essential role in the mitochondrial metabolism by its contribution to cellular redox homeostasis. Overstimulation of CYB5R3 associated with lipid rafts can account for the overshot of plasma membrane-focalized superoxide anion production that triggers the entry of CGN in the irreversible phase of apoptosis.
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