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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Catalog Number:
(89351-256)
Supplier:
Genetex
Description:
SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
Supplier:
Spectrum Chemicals
Description:
BHT, Granular, FCC is used in small quantities as a food additive as an antioxidant. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(TCB2775-100MG)
Supplier:
TCI America
Description:
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal Specific rotation [a]20/D: 17 deg (C=1, H2O) Molecular Formula: C18H24N2
Catalog Number:
(10087-792)
Supplier:
Proteintech
Description:
GPR35, also named as KYNA receptor, belongs to the G-protein coupled receptor 1 family. GPR35 acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of GPR35 is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins . This antibody is specific to GPR35.
Supplier:
CHARLES RIVER LABORATORIES
Description:
This human stem cell portfolio includes hematopoietic CD34+ stem cell products as well as pluripotent stem cells.
Catalog Number:
(CA89050-498)
Supplier:
Spectrum Chemicals
Description:
Urea, USP, JP is used in topical dermatological products to promote rehydration of the skin. Urea preparations are also used for non-surgical removal of damaged or dead nails. All Spectrum Chemical USP, JP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(103006-282)
Supplier:
Anaspec Inc
Description:
Angiotensin or Ang (1-7), DRVYIHP, is a cleavage product from either Angiotensin (Ang) I or Angiotensin (Ang) II. Ang (1-7) acts as a vasodilator, inhibitor of protein synthesis or as a natriuretic agent. Ang (1-7) acts through its G-protein coupled receptor, Mas.
Sequence: DRVYIHP MW: 899 Da % Peak area by HPLC: 95 Storage condition: -20°C
Catalog Number:
(76081-884)
Supplier:
Bioss
Description:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
Catalog Number:
(76085-096)
Supplier:
Bioss
Description:
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
Supplier:
DWK Life Sciences (KIMBLE)
Description:
Straight-sided shell vials are fabricated from clear N-51A borosilicate glass.
Catalog Number:
(10434-712)
Supplier:
Bioss
Description:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
Catalog Number:
(10447-852)
Supplier:
Bioss
Description:
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Catalog Number:
(75794-422)
Supplier:
Prosci
Description:
Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the cloned 28 kDa glycoprotein that is related to the p35 chain of IL-12. IL-27 is expressed by monocytes, endothelial cells and dendritic cells. IL-27 binds to and signals through a heterodimeric receptor complex composed of WSX1 (TCCR) and gp130. Evidence suggests IL-27 interacts only with WSX-1. IL-27 has both anti- and proinflammatory properties. As an antiinflammatory, IL-27 seems to induce a general negative feedback program that limits T and NK-T cell activity. At the onset of infection, IL-27 induces an IL-12 receptor on naie CD4+ T cells, making them susceptible to subsequent IL-12 activity (and possible Th1 development). Notably, IL-12 family cytokines are both induced and inhibited by bacterial products. Microbes promote IL-27 secretion through TLR4, and also block IL-27 production via C5a induction.
Catalog Number:
(10477-942)
Supplier:
Bioss
Description:
FAM36A is a multi-pass membrane protein. It belongs to the FAM36 family. The exact function of FAM36A remains unknown.Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM36A gene product has been provisionally designated FAM36A pending further characterization.
Catalog Number:
(76079-366)
Supplier:
Bioss
Description:
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalog Number:
(76079-728)
Supplier:
Bioss
Description:
This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells.
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