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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Supplier:
Bel-Art Products
Description:
For easy and continuous vacuum aspiration of a variety of liquids including tissue culture media, wash solutions, supernatant fluids after centrifugation, and chemical waste.
Catalog Number:
(10406-278)
Supplier:
Bioss
Description:
Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
Catalog Number:
(10837-120)
Supplier:
Bel-Art Products
Description:
Made of soft, clear, flexible vinyl that conforms to the face and nose, these goggles have four vents to reduce fogging.
Catalog Number:
(76007-400)
Supplier:
Remco Products
Description:
This brush is perfect for cleaning tools with exposed blades that could cause injury to the user.
Catalog Number:
(70680-186)
Supplier:
Bel-Art Products
Description:
Hollow Teflon® PTFE stoppers are designed for boiling and distilling flasks with ground joints.
Catalog Number:
(76338-114)
Supplier:
Marlin Steel Wire Products
Description:
Stainless steel material handling parts washing basket with four mesh openings per linear inch and handles for easy gripping.
Catalog Number:
(29876-001)
Supplier:
Bel-Art Products
Description:
Highly visible nylon indicator ball is housed in clear polycarbonate and rotates in circular channel during flow providing immediate visual indication of water/liquid flow.
Catalog Number:
(MSPP-780271997)
Supplier:
Stemcell Technologies
Description:
Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils, and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford <i>et al.</i>). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation, and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford <i>et al.</i>).
Supplier:
Ansell Healthcare
Description:
These polyethylene pharma covers provide product protection from environmental impurities during storage, processing and transportation.
Catalog Number:
(10405-092)
Supplier:
Bioss
Description:
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalog Number:
(CA610-446-042)
Supplier:
Rockland Immunochemical
Description:
This product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA), fluorescent western blotting and is also suitable for multiplex analysis with multicolor imaging.
Catalog Number:
(76271-420)
Supplier:
Harvard Apparatus
Description:
Reusable Oocyte Petri electrodes are ideal for electroporation of oocytes, embryos or other cell types in small volumes.
Catalog Number:
(76006-960)
Supplier:
Remco Products
Description:
This nylon flexible handle is used with a tube brush for cleaning around sensitive areas such as glass, and its flexibility allows it to follow curved pipes.
Supplier:
Spectrum Chemicals
Description:
L-Glutamic Acid, FCC - The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(103006-274)
Supplier:
Anaspec Inc
Description:
This product contains 0.03 mg (net) of the 32 CEF peptides for a total of 1 mg in one vial. Used in the stimulation of IFNγ release from CD8+ T cells in individuals with defined HLA types, these epitopes are useful in applications such as ELISPOT, intracellular cytokine and CTL assays.
% peak area by HPLC: ≥ 95 Storage condition: -20°C
Catalog Number:
(10446-916)
Supplier:
Bioss
Description:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf63 gene product has been provisionally designated C1orf63 pending further characterization.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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