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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Catalog Number:
(10390-170)
Supplier:
Bioss
Description:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Supplier:
Spectrum Chemicals
Description:
Acacia, Spray-Dried Powder, NF is an excipient binder.
Supplier:
DWK Life Sciences (KIMBLE)
Description:
All vials may appear to be created equal, but quality and performance make the difference when analyzing vital samples. MicroLiter vials are identical, clean, dependable vials, certified to ensure optimal performance and reproducible results.
Catalog Number:
(10388-210)
Supplier:
Bioss
Description:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.
Catalog Number:
(10388-212)
Supplier:
Bioss
Description:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.
Catalog Number:
(10371-036)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Supplier:
Bel-Art Products
Description:
Keep bags open and securely supported on these economical, lightweight, stainless steel wire frames.
Supplier:
ELECTRON MICROSCOPY SCIENCE
Description:
The continuous ultrathin film on lacey film allows for the thinnest support film that still has adequate strength to withstand specimen preparation. The film (less than 3 nm thick) lies across a carbon lacey film supported by a 200, 300, or 400 mesh grid. This product is ideal for looking at nanotubes, virus particles and other small particulate material.
Supplier:
Technical Glass Products
Description:
Fused Quartz consists of high-purity Silica (SiO2) with a purity level of 99.998%
Catalog Number:
(75811-910)
Supplier:
Spectrum Chemicals
Description:
Potassium Iodide, Granular, FCC is used as a source for dietary iodine. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(76085-802)
Supplier:
Bioss
Description:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
Catalog Number:
(76109-116)
Supplier:
Bioss
Description:
This gene is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. This gene encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation. This duplicated region contains a complete copy of the short splice variant of the BOLA2 gene and a partial copy of the long splice variant of the BOLA2 gene.
Catalog Number:
(TWTX1067)
Supplier:
Texwipe
Description:
These convenient wipers provide portion control and reduced potential of spillage in and out of the cleanroom.
Supplier:
HARDY DIAGNOSTICS CA
Description:
CRITERION™ Standard Methods Agar (Plate Count Agar) is recommended for use in determining the microbial content in dairy products, food, water and other material of sanitary importance
Supplier:
Bel-Art Products
Description:
This one-piece cylinder with handle provides a secure, solid grip for safer pouring.
Catalog Number:
(CA100-101-230)
Supplier:
Rockland Immunochemical
Description:
A working dilution of 1:2,000 to 1:10,000 of the reconstitution concentration is suggested for this product.
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