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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Supplier:
Prosci
Description:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive.
Catalog Number:
(76079-086)
Supplier:
Bioss
Description:
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Supplier:
New England Biolabs (NEB)
Description:
OneTaq Quick-Load DNA Polymerase is an optimized, ready-to-use blend of Taq and Deep Vent DNA Polymerases ideally suited to routine PCR applications from a variety of templates, including pure DNA solutions, bacterial colonies and cDNA products.
Catalog Number:
(10103-314)
Supplier:
Prosci
Description:
Similarity to a transcriptional repressor suggests that C21orf66 is involved in the regulation of transcription. Alternative splicing of this gene results in three transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. Similarity to a transcriptional repressor suggests that this gene's protein product is involved in the regulation of transcription. Alternative splicing of this gene results in three transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Catalog Number:
(CA610-4102)
Supplier:
Rockland Immunochemical
Description:
Secondary antibody reagents are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level
Catalog Number:
(10467-636)
Supplier:
Bioss
Description:
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].
Catalog Number:
(CA100-401-A01)
Supplier:
Rockland Immunochemical
Description:
This antibody reacts with human Cul1 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated product and Protein from cell lysates (using HeLa or NIH-3T3).
Catalog Number:
(CA600-405-466)
Supplier:
Rockland Immunochemical
Description:
This product has been assayed against 1.0 µg of KLH in a standard capture ELISA using pNPP p-nitrophenyl phosphate as a substrate for 30 minutes at room temperature.
Supplier:
KEYSTONE ADJUSTABLE CAP CO., INC.
Description:
Ready to use gamma irradiated pens and markers eliminate the risks associated with surface sanitization procedures.
Catalog Number:
(10488-414)
Supplier:
Bioss
Description:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(10332-704)
Supplier:
Bioss
Description:
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Catalog Number:
(10665-078)
Supplier:
Bioss
Description:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Catalog Number:
(10488-418)
Supplier:
Bioss
Description:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
Supplier:
Bel-Art Products
Description:
Low-cost, sturdy scoop ideal for general laboratory use with high sides to prevent spillage.
Supplier:
Bel-Art Products
Description:
Great economical solution for safe disposal of used pipettes, Petri dishes, multi-well cell culture plates, cell culture flasks, culture plates, membrane filters and other biohazard wastes.
Catalog Number:
(RK30007)
Supplier:
Restek
Description:
Mix contains: Benzene (71-43-2), Carbon disulfide (75-15-0), Ethylbenzene (100-41-4), Toluene (108-88-3), vinyl acetate (108-05-4), o-Xylene (95-47-6), p-Xylene (106-42-3).
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