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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Supplier:
Spectrum Chemicals
Description:
Sodium Ascorbate, FCC is used as a food additive as an antioxidant and acidity regulator. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(CA1.10582.0500)
Catalog Number:
(CA1.05463.0500)
Catalog Number:
(102979-174)
Supplier:
Adipogen
Description:
Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in microbial DNA via the Toll-like receptor (TLR) 9 if the CpG ODN were free of additional immune stimulatory contaminants often present in synthetic commercial CpG ODN preparations designed for molecular biology applications (i.e. PCR). Given that high quality CpG ODNs were used, a close link has been established between the expression of TLR9 on certain immune cell subsets and the modulation of the immune system by CpG DNA. Different types of CpG ODNs were identified based on their differing biological effects on different cell types: ODN Type A is a potent inducer of IFN-alpha in human PDC, (i.e. ODN 1585 or 2216) leading to antigen presenting cell (APC) maturation, whereas ODN Type B (i.e. ODN 2006 or ODN 1668 / ODN 1826) is a weak inducer of IFN-alpha but rather stimulates IL-8 production and increasing costimulatory and Ag-presenting molecules and triggers proliferation of B-cells and IgM and IL-6 production. A third type of CpG ODN has been identified, termed ODN Type C, with both high induction of INF-alpha in PDC and activation of B-cells. The sequence of CpG Type C (also called K) (i.e. ODN 2395 or M362) combines elements of both Type A and Type B and contains a central palindromic sequence with CG dinucleotides, a characteristic feature of Type A, and a TCGTCG motif at the 5' end, present in Type B CpG ODNs. Although the CpG motifs are thought to differ between mice and humans, in both species the recognition of CpG ODNs is mediated by TLR9. The optimal CpG motif in humans is GTCGTT and GACGTT for the murine sequence. However, recent evidence suggests that this sequence specificity is restricted to phosphorothioate (PS)-modified ODN and is not observed when a natural phosphodiester backbone is used. In recent years sequence requirements, specificity, signaling pathways and kinetics of the TLR9 suppression by inhibitory ODNs (iODNs) have been investigated.
Supplier:
APEX ASEPTIC PRODUCTS, LLC.
Description:
Sterile sleeve covers made with Dupont® Tyvek™ fabrics and are suitable for cleanroom use.
Catalog Number:
(CAPIPA5-18822)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with canine, mouse and rat based on sequence homology. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Catalog Number:
(CAPIPA5-18608)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with canine, mouse and rat based on sequence homology. This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
Catalog Number:
(CAPIPA5-18892)
Supplier:
Thermo Scientific
Description:
This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase and peptidyl-alpha-hydroxyglycine alpha-amidating lyase . These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Catalog Number:
(CA11024-442)
Supplier:
Spectrum Chemicals
Description:
ZINC STEARATE, POWDER, USP is also referred to as 'Zinc Soap' and can be used in powders and ointments in the treatment of eczema, acne, and other skin diseases. It may also be used as a lubricant in cosmetic formulations to improve texture and smoothness. Zinc stearate has antiseptic, astringent and topical protective properties. Spectrum Chemical manufactured USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(CAPIPA5-18351)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
Catalog Number:
(CAPIPA5-18481)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Catalog Number:
(76488-320)
Supplier:
APEX ASEPTIC PRODUCTS, LLC.
Description:
Sterile LiquidGuard™ sleeve covers are suitable for cleanroom use.
Catalog Number:
(CA10662-162)
Supplier:
Hach
Description:
Automatic titration without all the complications.
Catalog Number:
(CA89407-742)
Supplier:
HARDY DIAGNOSTICS CA
Description:
A sterile Triphenyl tetrazolium chloride solution. TTC Solution 1%, use this product with Motility Medium S Base (89405-754). TTC Solution .05% is used to supplement Criterion™ Tergitol-7 Agar, 89406-120, for the enumeration of coliforms in food and water supplies.
Catalog Number:
(CAPIPA5-18964)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, canine and human based on sequence homology. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members . A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Catalog Number:
(CAPIPA5-18026)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with mouse and rat based on sequence homology. Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
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