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Isolation+and+Cleanup+HyClone+products+(Cytiva)
Supplier:
CUBE BIOTECH
Description:
Sulfo-SMA is an electroneutral modification of existing SMAs. It does not interfere with charge-sensitive interactions between proteins and lipids. This innovation opens up a wider range of experimental research in terms of charge-sensitive membrane protein processes like protein-protein and protein-lipid interactions. In addition, Sulfo-SMA belongs to a new generation of SMA’s which are RAFT polymerized. This achieves a reduction in both monomer size and greater monodispersity.
Another significant advantage of Sulfo polymers compared to other polymers is the wide pH range in which they remain stable. The buffer in which the polymer is supplied has a pH of 7.5, but the polymer itself remains stable between pH 4 and pH 10. The special physicochemical properties of Sulfo-SMAs make them ideal for cryo-TEM and other downstream applications. After successful membrane protein solubilization, the protein can be purified using affinity chromatography. For membrane protein purification, we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose. Good publications to find details about Sulfo-SMA and Sulfo-DIBMA are: Glueck et al. (2022) Janson et al. (2022) Eggenreich et al. (2023)
Supplier:
AVANTOR PERFORMANCE MATERIAL LLC
Description:
Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives. All the products are cGMP produced and meet USP grade standards.
Catalog Number:
(CA1.15108.0500)
Catalog Number:
(89012-496)
Supplier:
Vetequip
Description:
This anesthesia center is ideal for high-volume, assembly-line type procedures
Catalog Number:
(CAPIPA5-15072)
Supplier:
Thermo Scientific
Description:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2); mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Catalog Number:
(76226-080)
Supplier:
Rockland Immunochemical
Description:
Conjugated Anti-Monkey IgG (H&L) DyLight™ 680 Conjugated antibody generated in rabbit detects specifically monkey IgG heavy and light chains. Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. IgG binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. The whole IgG molecule possesses both the F(c) region, recognized by high-affinity Fc receptor proteins, as well as the F(ab) region possessing the epitope-recognition site. Both heavy and light chains of the antibody molecule are present. This DyLight™680 conjugated anti-Monkey IgG (H&L) secondary antibody is ideal for investigators who routinely perform immunofluorescence, flow cytometry, and more general immunoassays. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment. The emission spectra for this DyLight™ conjugate match the principle output wavelengths of most common fluorescence instrumentation.
Supplier:
JAC
Description:
Racks are constructed of PETG plastic with a white acrylic base, except for 30109-506 which is made of autoclavable polypropylene
Catalog Number:
(CAD400-03-0050)
Supplier:
Rockland Immunochemical
Description:
Plasma is obtained from non-hemolyzed blood collected from healthy, fasted donors
Catalog Number:
(TCG0137-001G)
Supplier:
TCI America
Description:
Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: H-Gly-Pro-OH
Supplier:
ED SPELDY EAST CO. LTD. CA
Description:
Preserved bat in resin material.
Catalog Number:
(TCG0112-001G)
Supplier:
TCI America
Description:
Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: H-Gly-DL-Ala-OH
Supplier:
Tonbo Biosciences
Description:
The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells. The SK7 antibody is a widely used phenotypic marker for human T cells. This antibody may induce T cell activation in the presence of monocytes. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Binding of clone SK7 can be blocked by an alternative Anti-Human CD3 clone, OKT3. Please choose the appropriate format for each application.
Catalog Number:
(10488-760)
Supplier:
Bioss
Description:
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
Catalog Number:
(76108-942)
Supplier:
Bioss
Description:
CCDC18, also known as NY-SAR-41 or dJ717I23.1, is a 1,454 amino acid protein expressed as two isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Supplier:
StemBioSys
Description:
CELLvo™ XF Matrix is a ready-to-use cell culture substrate which provides a xeno-free native microenvironment that replicates the 3-dimensional "home" in which stem cells naturally reside and proliferate.
Supplier:
MOLECULAR DEVICES LLC. CA
Description:
SpectraMax®, Onsite essential protection service plan for Spectramax® 190
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