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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(CAPIPA5-17933)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(75789-610)
Supplier:
Prosci
Description:
T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.
Catalog Number:
(10390-750)
Supplier:
Bioss
Description:
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008].
Catalog Number:
(10402-852)
Supplier:
Bioss
Description:
The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.
Catalog Number:
(470149-070)
Supplier:
OSAW INDUSTRIAL PRODUCTS SE
Description:
Build five different power supplies by connecting clip leads to one of the five color-coded terminals.
Supplier:
Waring Products
Description:
1L container. For Two-Speed and Seven-Speed Waring* Laboratory Blenders.
Catalog Number:
(76262-628)
Supplier:
Rockland Immunochemical
Description:
Anti-Leptin antibody detects leptin protein. Leptin may function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Obesity associated leptin is the product of the OB gene and has been identified with Type II diabetes. Anti-leptin Antibody is ideal for investigators involved in Cell Signaling, Obesity research, aging research and Signal Transduction research.
Catalog Number:
(20000-713)
Supplier:
PIP
Description:
Combination of comfortable nylon shell, and a protective PU coating makes this glove ideal for use in electronic and computer assembly, quality control, inspection and general assembly.
Catalog Number:
(CAPIPA525990)
Supplier:
Thermo Scientific
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Supplier:
G-Biosciences
Description:
A proprietary mixture of Formaldehyde, EDTA and Blue Dextran that is designed for use in loading DNA samples onto denaturing polyacrylamide gels.
Catalog Number:
(CA89500-938)
Supplier:
Hach
Description:
PTFE anti diffusion titrant delivery tip for use mounted on delivery tubing.
Catalog Number:
(CAPIPA5-12572)
Supplier:
Thermo Scientific
Description:
This antibody is predicted to react with bovine, hamster, mouse and rat based on sequence homology. Cdk2 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Catalog Number:
(CA700011-956)
Supplier:
Spectrum Chemicals
Description:
Stearic Acid, Type 50, Powder, NF is used as an emulsifying agent, solubilizing agent, tablet and capsule lubricant. The NF grade indicates it is graded suitable for personal care, cosmetic and pharmaceutical applications. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(89296-262)
Supplier:
Genetex
Description:
Goat polyclonal antibody to CYB5R3 / Dia 1 (mouse)
Catalog Number:
(89296-972)
Supplier:
Genetex
Description:
Goat polyclonal antibody to Fibroblast growth factor 21
Catalog Number:
(76101-064)
Supplier:
Bioss
Description:
DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
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