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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(10488-508)
Supplier:
Bioss
Description:
With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The C5orf35 gene product has been provisionally designated C5orf35 pending further characterization.
Catalog Number:
(10491-134)
Supplier:
Bioss
Description:
Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf28 gene product has been provisionally designated C7orf28 pending further characterization.
Catalog Number:
(10092-584)
Supplier:
Proteintech
Description:
Polycystin 2 (PKD2), the product of the gene mutated in type 2 autosomal dominant polycystic kidney disease, belongs to the polycystin family. PKD2 is a ~110-kDa six-transmembrane channel protein with cytoplasmic N- and C-termini. This protein functions as a Ca2+-activated intracellular Ca2+ release channel in the endoplasmic reticulum. It is also present in the plasma membrane, where it functions as a nonselective cation channel. In addition, PKD2 expression has been documented in the primary cilium of kidney epithelial cells, where it is believed to have an essential role in mediating Ca2+ entry in response to flow rate changes, suggesting that it may be part of a mechanosensing machinery residing in the primary cilium.
Catalog Number:
(75812-342)
Supplier:
Spectrum Chemicals
Description:
Sorbic Acid, Powder, FCC is used as a food preservative. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(CA80500-380)
Supplier:
MilliporeSigma
Description:
The SpinPrep™ Gel DNA Kit enables efficient extraction of DNA fragments of 150 bp to > 12,000 bp in size from agarose gels.
Catalog Number:
(89331-202)
Supplier:
Genetex
Description:
Purity: Purified by protein A chromatography or sequential differential precipitations Species Reactivity: Virus Tested Applications: HI, ICC/IF Pkg Size: 500 ul
Catalog Number:
(89271-196)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to HTRA3
Catalog Number:
(89349-266)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to DDT (D-dopachrome tautomerase)
Catalog Number:
(89320-040)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Snurportin 1 (snurportin 1)
Catalog Number:
(89335-336)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to cystatin F (cystatin F (leukocystatin))
Catalog Number:
(89335-450)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to EDAR (ectodysplasin A receptor)
Catalog Number:
(89357-588)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to PDYN (prodynorphin)
Catalog Number:
(89331-708)
Supplier:
Genetex
Description:
Clone: 0119 Purity: Purified by protein A chromatography or sequential differential precipitations Species Reactivity: Virus Tested Applications: ICC/IF Pkg Size: 500 ul
Catalog Number:
(10350-360)
Supplier:
Bioss
Description:
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Catalog Number:
(10748-792)
Supplier:
Prosci
Description:
CDC42 Antibody: CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
Catalog Number:
(10081-910)
Supplier:
Proteintech
Description:
Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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