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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(89416-072)
Supplier:
Prosci
Description:
Cyclin O Antibody: Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member.
Catalog Number:
(10405-282)
Supplier:
Bioss
Description:
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.
Catalog Number:
(10433-650)
Supplier:
Bioss
Description:
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(10420-972)
Supplier:
Bioss
Description:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
Supplier:
Biotium
Description:
This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number:
(10490-470)
Supplier:
Bioss
Description:
C9orf153 is a 101 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf153 maps to human chromosome 9q21.33. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Catalog Number:
(89274-274)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [2H5] to C21orf59
Catalog Number:
(89274-342)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [7B5] to BTN1A1
Catalog Number:
(89304-400)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to BRCA1 (Phospho Ser1423)
Catalog Number:
(89271-888)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [7G10] to SULT2A1
Catalog Number:
(89298-578)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [k1G6 ] to PPM1G
Catalog Number:
(89304-210)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to p90 RSK1 (phospho Ser352)
Catalog Number:
(89281-962)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to PKD (phospho Ser910)
Supplier:
HiMedia
Description:
HL extract powder is processed under controlled conditions to retain all the nutritive values of liver. It is incorporated in media which are used for the growth of fastidious anaerobic organisms.
Catalog Number:
(KT570010-0250)
Supplier:
DWK Life Sciences (KIMBLE)
Description:
Developed for the concentration of trace amounts of sample dissolved in organic solvents
Catalog Number:
(89354-146)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to AIMP1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1)
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