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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(10490-920)
Supplier:
Bioss
Description:
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf1 gene product has been provisionally designated C6orf1 pending further characterization.
Catalog Number:
(10490-848)
Supplier:
Bioss
Description:
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf64 gene product has been provisionally designated C6orf64 pending further characterization.
Catalog Number:
(10493-224)
Supplier:
Bioss
Description:
Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The C13orf28 gene product has been provisionally designated C13orf28 pending further characterization.
Catalog Number:
(10496-322)
Supplier:
Bioss
Description:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
Catalog Number:
(89349-190)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to PGD (phosphogluconate dehydrogenase)
Catalog Number:
(89349-158)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to AChE (acetylcholinesterase)
Catalog Number:
(89319-532)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to CD97 (CD97 molecule)
Catalog Number:
(89355-600)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Profilin 2 (profilin 2)
Catalog Number:
(89320-534)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to KIDINS220
Catalog Number:
(89318-330)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Amphiregulin (amphiregulin)
Catalog Number:
(89320-784)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Drebrin (drebrin 1)
Catalog Number:
(89354-914)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to ALOXE3 (arachidonate lipoxygenase 3)
Catalog Number:
(89319-950)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to PANK3 (pantothenate kinase 3)
Catalog Number:
(89319-964)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to AK8 (adenylate kinase 8)
Catalog Number:
(89335-370)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Factor B (complement factor B)
Catalog Number:
(89350-490)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to 5-HT1A receptor
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