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chromatography+columns+HyClone+products+(Cytiva)


72,348  results were found

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Supplier:  Biotium
Description:   This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Supplier:  Biotium
Description:   This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Supplier:  Bioss
Description:   Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.
Catalog Number: (89349-772)

Supplier:  Genetex
Description:   Rabbit polyclonal antibody to Nidogen (nidogen 1)
Catalog Number: (89296-164)

Supplier:  Genetex
Description:   Goat Polyclonal antibody to Zyxin
Catalog Number: (89303-644)

Supplier:  Genetex
Description:   Goat polyclonal antibody to Cytochrome b reductase 1
Catalog Number: (89303-624)

Supplier:  Genetex
Description:   Goat polyclonal antibody to Klotho
Supplier:  Bioss
Description:   CCDC17, also known as FLJ17921 or RP4-697E16.4, is a 622 amino acid protein expressed as four isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Catalog Number: (10107-088)

Supplier:  Prosci
Description:   The function remains unknown.
Catalog Number: (89358-150)

Supplier:  Genetex
Description:   The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. [provided by RefSeq]
Catalog Number: (89319-420)

Supplier:  Genetex
Description:   Rabbit Polyclonal antibody to GSPT1 (eukaryotic peptide chain release factor GTP-binding subunit ERF3A)
Catalog Number: (10104-638)

Supplier:  Prosci
Description:   This gene, which is located on chromosome 20, is predicted to encode for a signal protein with unknown function.
Catalog Number: (CA77575-234)

Supplier:  PerkinElmer
Description:   The CRISPRclean® stranded total RNA prep with rRNA depletion (HMR + pan bacteria) is a total RNA library prep leveraging a CRISPR-powered workflow facilitating the detection of lower expressing and biologically relevant transcripts from complex samples.
New Product
Catalog Number: (89352-592)

Supplier:  Genetex
Description:   The affinity purified anti IgM mu antibodies only react with IgM by immunodiffusion and Immunoelectrophoretic and ELISA techniques. Goats were immunized with highly purified normal mouse IgM in Freund's adjuvant. The antiserum was solid phase absorbed to make it IgM mu chain specific and the anti mu chain antibodies were isolated by solid phase immunoaffinity chromatography
Supplier:  AGILENT TECHNOLOGIES, INC (CSD) CA
Description:   Agilent skimmer cones ensure the performance that single & triple quadrupole ICP-MS systems demand.
Catalog Number: (89297-732)

Supplier:  Genetex
Description:   Goat polyclonal antibody to NANOS1
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