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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(89320-226)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to DPP2(DPP7) (dipeptidyl-peptidase 7)
Catalog Number:
(89350-400)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to GAL3ST1 (galactose-3-O-sulfotransferase 1)
Catalog Number:
(89319-810)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Drebrin (drebrin 1)
Catalog Number:
(89349-442)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to ADAMTSL2 (ADAMTS-like 2)
Catalog Number:
(89320-034)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to PTCH1 (patched homolog 1 (Drosophila))
Catalog Number:
(76109-358)
Supplier:
Bioss
Description:
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.
Supplier:
AGILENT TECHNOLOGIES, INC (CSD) CA
Description:
Sampler, skimmer, hyper skimmer cones, & supplies for PerkinElmer NexION & ELAN ICP-MS instruments.
Catalog Number:
(103318-704)
Supplier:
Novus Biologicals
Description:
The CD21 Antibody (7D6) from Novus Biologicals is a mouse monoclonal antibody to CD21. This antibody reacts with human. The CD21 Antibody (7D6) has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Frozen.
Catalog Number:
(10368-132)
Supplier:
Bioss
Description:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013].
Catalog Number:
(10372-378)
Supplier:
Bioss
Description:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013].
Catalog Number:
(89330-558)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to KCNS2 (potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2)
Catalog Number:
(89330-386)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to APOBEC3C (probable DNA dC->dU-editing enzyme APOBEC-3C)
Catalog Number:
(89354-090)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2)
Catalog Number:
(10109-114)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(10109-328)
Supplier:
Prosci
Description:
The function remains unknown.
Catalog Number:
(76101-746)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades; isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
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