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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(89417-046)
Supplier:
Prosci
Description:
AFAP1L2 Antibody: AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites. It interacts with and is phosphorylated by c-Src tyrosine kinase. Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions. Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer. Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy. At least four isoforms of AFAP1L2 are known to exist.
Supplier:
Omega Bio-Tek
Description:
Omega Bio-teks Mag-Bind SeqDTR is designed to effective and reliable removal of unincorporated terminators from sequencing reaction. The system combines Omega Bio-teks proprietary chemistry with the reversible nucleic acid-binding properties of paramagnetic beads to eliminate excess nucleotides, primers, salts, and unicorporated dye terminators.
Catalog Number:
(89300-650)
Supplier:
Genetex
Description:
Rabbit polyclonal to DHRS3 (Internal)
Catalog Number:
(89301-382)
Supplier:
Genetex
Description:
Rabbit polyclonal to HAO1 (Internal)
Catalog Number:
(89301-154)
Supplier:
Genetex
Description:
Rabbit polyclonal to IGH (C-Term)
Catalog Number:
(89301-070)
Supplier:
Genetex
Description:
Rabbit polyclonal to COL18A1 (N-term)
Catalog Number:
(89355-794)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to C/EBP epsilon (CCAAT/enhancer binding protein (C/EBP), epsilon)
Catalog Number:
(CA76415-418)
Supplier:
Omega Bio-Tek
Description:
Isolate viral RNA from nasopharyngeal swab specimens (dry or in VTM) using magnetic beads.
Catalog Number:
(89301-286)
Supplier:
Genetex
Description:
Rabbit polyclonal to ALKBH3 (C-term)
Catalog Number:
(89302-308)
Supplier:
Genetex
Description:
Rabbit polyclonal to FTO (N-term)
Catalog Number:
(89301-978)
Supplier:
Genetex
Description:
Rabbit polyclonal to ADAMTS4 (C-term)
Catalog Number:
(89300-818)
Supplier:
Genetex
Description:
Rabbit polyclonal to SPRR1B (C-term)
Catalog Number:
(10111-796)
Supplier:
Prosci
Description:
DMTF1 binds specifically to the nonamer DNA consensus sequences CCCG (G/T)ATGT to activate transcription.
Catalog Number:
(89294-114)
Supplier:
Genetex
Description:
Goat polyclonal antibody to INDO / IDO
Catalog Number:
(76082-116)
Supplier:
Bioss
Description:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
Catalog Number:
(77269-192)
Supplier:
TRITON PRODUCTS TE
Description:
DuraBoard® is the most durable, weather and impact resistant pegboard available. It is eight times stronger than conventional pegboard.
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