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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(10748-538)
Supplier:
Prosci
Description:
TOLLIP Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
Catalog Number:
(10407-138)
Supplier:
Bioss
Description:
Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
Catalog Number:
(10231-504)
Supplier:
Bioss
Description:
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Catalog Number:
(10405-090)
Supplier:
Bioss
Description:
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalog Number:
(10814-044)
Supplier:
Prosci
Description:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Supplier:
Shenandoah Biotechnology
Description:
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).
Catalog Number:
(103003-898)
Supplier:
Anaspec Inc
Description:
c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope.
Sequence:EQKLISEEDL MW:1203.3 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(700011-264)
Supplier:
Spectrum Chemicals
Description:
KERATIN, POWDER is the key material that makes up the human body’s out layer of skin. It is also the key element of hair and nails. It is considered to be similar to chitin. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.
Catalog Number:
(13197-418)
Supplier:
Bel-Art Products
Description:
Designed for mixing liquids in large vats and tanks, this high-density polyethylene stirring paddle has a 91 cm (3') handle.
Supplier:
BioFit
Description:
Bridgeport Series chairs boast a number of features and benefits that make them a popular choice for laboratory, healthcare, education and technical workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.
Supplier:
BioFit
Description:
Bridgeport Series chairs boast a number of features and benefits that make them a popular choice for laboratory, healthcare, education and technical workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.
Supplier:
PeproTech, Inc.
Description:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.
Catalog Number:
(10748-608)
Supplier:
Prosci
Description:
MD-1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Supplier:
KOFLO CORPORATION
Description:
Calibration columns provide a simple, economical method for checking pump flow rates.
Supplier:
Mortech Manufacturing
Description:
Mopec’s range of Harmony tissue marking dyes are used to permanently mark surgical tissue margins in Histological specimens. Marking dyes are available in nine colors, with a standardized viscosity over the range. This ensures that there is less variation in viscosity from one color to another as compared to competitor products and allows the easy marking of both small and large specimens with any chosen color.
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