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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(76109-248)
Supplier:
Bioss
Description:
The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component.Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex. Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, especially in the induction of the IL-2and IL-4. Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene.
Catalog Number:
(76110-984)
Supplier:
Bioss
Description:
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
Catalog Number:
(10350-908)
Supplier:
Bioss
Description:
This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Catalog Number:
(76085-398)
Supplier:
Bioss
Description:
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Catalog Number:
(76080-116)
Supplier:
Bioss
Description:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors.
Catalog Number:
(10350-916)
Supplier:
Bioss
Description:
This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Supplier:
Optimize
Description:
Biocompatible and chemically inert to most commonly-used solvents tubing.
Catalog Number:
(CA200-403-095)
Supplier:
Rockland Immunochemical
Description:
This product has been assayed against 1.0 µg of Streptavidin in a standard capture ELISA using ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])
Supplier:
Spectrum Chemicals
Description:
Chlorobutanol, Anhydrous, NF is a very effective preservative in many pharmaceutical products for eyes, ears and nose, dental preparations. The anhydrous form is useful in formulations where the absence of water is desired. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(102981-584)
Supplier:
Adipogen
Description:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of goats immunized with highly pure Recombinant Murine M-CSF. AntiMurine M-CSFspecific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
BioFit
Description:
BioFit multipurpose carts are specially designed to transport and store media, equipment and supplies in a variety of work and training spaces.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of goats immunized with highly pure Recombinant Human SCGF-β. AntiHuman SCGF-βspecific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-9. AntiMurine IL-9specific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human TFF-2. AntiHuman TFF-2specific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of goats immunized with highly pure Recombinant Rat IL-6. AntiRat IL-6specific antibody was purified by affinity chromatography and then biotinylated.
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